1.

The presence of ______ signal peptides can significantly compromise the prediction _______ because the programs tend to confuse hydrophobic signal peptides with membrane helices.(a) hydrophobic, accuracy(b) hydrophobic, error(c) hydrophilic, accuracy(d) hydrophilic, error

Answer» Correct option is (a) hydrophobic, accuracy

Explanation: Predicting transmembrane helices is relatively easy. The accuracy of Some of the best predicting programs, such as TMHMM or HMMTOP, can exceed 70%. To minimize errors, the presence of signal peptides can be detected using a number of specialized programs and then manually excluded.


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