The rate at which monolithic devices transfer drugs to the patient body is proportional to _______________ of time.(a) Square of time(b) The square root of time(c) Twice the time(d) Half the timeI got this question in an international level competition.I need to ask this question from Biopharmaceuticals topic in division Biopharmaceuticals of Drug Biotechnology

The rate at which monolithic devices transfer drugs to the patient bod

1.	The rate at which monolithic devices transfer drugs to the patient body is proportional to _______________ of time.(a) Square of time(b) The square root of time(c) Twice the time(d) Half the timeI got this question in an international level competition.I need to ask this question from Biopharmaceuticals topic in division Biopharmaceuticals of Drug Biotechnology
Answer» Right OPTION is (b) The square root of time For explanation: The drug RELEASE from the matrix system of the monolithic device is rapid INITIALLY and FALLS as the matrix gets depleted. The rate is thus proportional to the square root of time. The polymers EMPLOYED for matrix system may be hydrophilic or lipophilic.

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