What are the characteristics of Matrix diffusion-controlled release systems?(a) Release the drug along the entire length of GIT(b) Drug disperse in an insoluble matrix of rigid hydrophobic materials(c) Release only at a specific drug(d) Employ waxes to control the rate of dissolutionI have been asked this question in examination.Question is taken from Biopharmaceuticals in section Biopharmaceuticals of Drug Biotechnology

What are the characteristics of Matrix diffusion-controlled release sy

1.	What are the characteristics of Matrix diffusion-controlled release systems?(a) Release the drug along the entire length of GIT(b) Drug disperse in an insoluble matrix of rigid hydrophobic materials(c) Release only at a specific drug(d) Employ waxes to control the rate of dissolutionI have been asked this question in examination.Question is taken from Biopharmaceuticals in section Biopharmaceuticals of Drug Biotechnology
Answer» Right choice is (b) Drug DISPERSE in an insoluble MATRIX of rigid HYDROPHOBIC materials The best I can explain: In this system, the drug is dispersed into an insoluble matrix of a rigid nonswellable hydrophobic material or swellable hydrophilic material. Materials such as insoluble plastic PVC and FATTY ACIDS are used as rigid matrix. The drug is generally kneaded with the plastic material.

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