What are the characteristics of the monolithic devices?(a) The drug has a large therapeutic index(b) Aqueous solutions(c) Control drug release by partitioning the drug from the oil(d) Administration of emulsionsI got this question in semester exam.My enquiry is from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

What are the characteristics of the monolithic devices?(a) The drug ha

1.	What are the characteristics of the monolithic devices?(a) The drug has a large therapeutic index(b) Aqueous solutions(c) Control drug release by partitioning the drug from the oil(d) Administration of emulsionsI got this question in semester exam.My enquiry is from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology
Answer» Right option is (a) The DRUG has a large therapeutic index The explanation is: Monolithic devices are USED when the rate of drug diffusion from the device is higher than the rate of drug permeation through the STRATUM corneum. There are TWO categories of matrix devices one is where the drug is dissolved in the polymer matrix and the other is where the drug is dispersed.

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