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What is acylation? Give example.

Answer»

SOLUTION :Most of amines REACT with acid chlorides, ANHYDRIDES and ESTERS by nucleophillic SUBSTITUTION reaction. This reaction is known as acylation.
Ex: (i) `C_(2)H_(5)NH_(2)+CHCOCl""tounderset("N-Ethylethanamide")(C_(2)H_(6)NH-CO-CH_(3))`
(ii) `C_(6)H_(5)NH_(2)+(CH_(3)CO)_(2)tounderset("N-Phenylethanamide")(C_(6)H_(5)NHCOCH_(3))+CH_(3)COOH`


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