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What Is Lyophilization? |
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Answer» Lyophilization, or freeze drying, there is a water is frozen, followed by its removal from the sample, INITIALLY by sublimation (primary drying) and then by desorption (secondary drying). In this PROCESS, the moisture content of the product is reduced to such a low level that does not support biological growth or chemical reactions which gives the stability to the FORMULATION. This technique USEFUL in formulation development of DRUGS which are thermolabile and/or unstable in aqueous medium. Lyophilization, or freeze drying, there is a water is frozen, followed by its removal from the sample, initially by sublimation (primary drying) and then by desorption (secondary drying). In this process, the moisture content of the product is reduced to such a low level that does not support biological growth or chemical reactions which gives the stability to the formulation. This technique useful in formulation development of drugs which are thermolabile and/or unstable in aqueous medium. |
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