1.

What is the difference between coformation and configuration in open chain molecules?

Answer»

Solution :Stereo isomers are of two types : 1) Configurational iomers 2) Conformational isomers.
Difference : Configurational isomers possess certain types of rigidity in the molecules. These molecules can be interconverted only by bond breaking and reforming new bods.
Conformation can be easily interconverted by simply rotating about `C-C` sigma bonds.
Explanation:
Configurational isomers are oftwo types : A) GEOMETRICAL isomers and B) Option isomers.
A) Geometrical isomers : This is due to hte difference in the spatial ARRANGEMENT of groups about teh doubly bonded carbon atoms in the molecules.
EXx : Cis - 2- Butene and Trans -2- Butene

B) Optical isomers : This is due to the diffent spatial arrangements of FOUR different atoms or RADICALS in the MOLECULE.
Ex : `(+)` Lactc acid (1) and `(-)` Lactic acid (2)

Conformations: As a result or rotation about single `C-C` bond, the atoms or groups of a molecule assume different spatial arrangements. These different atomic arrangements are called 'conformations.'`
Ex : Eclipsed (E) and staggered (S) conformations of ethane.


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