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What is the full form of SAD?(a) Secure Assessing dose(b) Single Ascending Dose(c) Sodium Ascending Dose(d) Single Amount DoseI had been asked this question by my school principal while I was bunking the class.My doubt is from Controlled Release Medication in division Controlled Release Medication of Drug Biotechnology

Answer»

The correct answer is (b) SINGLE Ascending Dose

To explain: Single Ascending Dose studies are those in which small groups of SUBJECTS are GIVEN a single dose of the DRUG while they are observed and tested for a period of time and MAD is Multiple Ascending Dose studies are conducted to better understand the PHARMACOKINETICS & pharmacodynamics of multiple doses of the drug.



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