What is the role of calcium ions In muscle contraction ? – InterviewSolution

InterviewSolution

1.	What is the role of calcium ions In muscle contraction ?
Answer» Calcium ions bind to specific sites on the troponin component of thin (actin) filaments. As a result, conformational change occurs in the troponin molecules and the active sites of F- actin are exposed. These are the sites Specific to myosin head that shows Mg dependent ATPase activity. When calcium ions are pumped back into the sarcoplasmic reticulum, the troponin component becomes free to mask the active sites for myosin head. This leads to breakage of cross bridges and the actin filaments slide out of A – band.

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