Related InterviewSolutions

• All of the following statements about efficacy and potency are true EXCEPT: a) Efficacy is usually a more important clinical consideration than potency b) Efficacy is the maximum effect of a drug c) Potency is a comparative measure, refers to the different doses of two drugs that are needed to produce the same effect d) The ED50 is a measure of drug’s efficacy
• The substance binding to one receptor sub type as an agonist and to another as an antagonist is called: a) Competitive antagonist b) Irreversible antagonist c) Agonist-antagonist d) Partial agonist
• If an agonist can produce sub maximal effects and has moderate efficacy it’s called: a) Partial agonist b) Antagonist c) Agonist-antagonist d) Full agonist 
• If an agonist can produce maximal effects and has high efficacy it’s called: a) Partial agonist b) Antagonist c) Agonist-antagonist d) Full agonist 
• An agonist is a substance that: a) Interacts with the receptor without producing any effect b) Interacts with the receptor and initiates changes in cell function, producing various effects c) Increases concentration of another substance to produce effect d) Interacts with plasma proteins and doesn’t produce any effect 
• Therapeutic index (TI) is: a) A ratio used to evaluate the safety and usefulness of a drug for indication b) A ratio used to evaluate the effectiveness of a drugc) A ratio used to evaluate the bio availability of a drug d) A ratio used to evaluate the elimination of a drug 
• Target proteins which a drug molecule binds are: a) Only receptors b) Only ion channels c) Only carriersd) All of the above
• Idiosyncratic reaction of a drug is:a) A type of hypersensitivity reaction b) A type of drug antagonism c) Unpredictable, inherent, qualitatively abnormal reaction to a drug d) Quantitatively exaggerated response
• Characteristic unwanted reaction which isn’t related to a dose or to a pharma codynamic property of a drug is called: a) Idiosyncrasy b) Hypersensitivity c) Tolerance d) Teratogenic action 
• What does “affinity” mean? a) A measure of how tightly a drug binds to plasma proteins b) A measure of how tightly a drug binds to a receptor c) A measure of inhibiting potency of a drug d) A measure of bio availability of a drug