1.

Which compound in the following couples will react faster in S_(N)2displacement and why? (a) 1-Bromopentane or 2-bromopentane (b) 1-Bromo-2-methylbutane or 2-bromo-2-methylbutane.

Answer»

SOLUTION :(a) 1-Bromopentane or 2-bromopentane <BR> `CH_(3) - CH_(2) - CH_(2) - CH_(2) - CH_(2)Br "" CH_(3)CHBrCH_(2)CH_(2)CH_(3) `
1-bromopentane will REACT FASTER . 2-bromopentane FACES some steric hindrance.
(b) `underset("1-Bromo -2-methylbutane") (CH_(3) - CH_(2) - overset(CH_(3)) overset(|)CH - CH_(2) - Br)"" underset("2-Bromo -2-methylbutane ") (CH_(3) - CH_(2) - underset(Br) underset(|) overset(CH_(3)) overset(|) C - CH_(3)) `
1-bromo-2-methylbutane reacts faster in `S_(N)2` displacement. There will be steric hindrance in the second compound.


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