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Which of the following can be incorporated into a liposome?(a) Only drugs and viruses(b) Only Peptides and viruses due to similar characteristics(c) Only viruses(d) Drugs, peptides, viruses, bacteriaThis question was addressed to me during an internship interview.This interesting question is from Biopharmaceuticals in portion Biopharmaceuticals of Drug Biotechnology

Answer»

Right choice is (d) Drugs, peptides, viruses, bacteria

The explanation: A large variety of drugs, peptides or proteins including antibodies and viruses and bacteria can be incorporated into liposomes. Water-SOLUBLE drugs will be TRAPPED in the aqueous COMPARTMENT while the lipophilic ones are incorporated in the LIPID phase of liposomes. They are available in various sizes and have the ability to incorporate both water and lipid soluble drugs.



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