Which of the following drugs cannot be given as transdermal administration?(a) Drugs with very short half-lives(b) Drugs with narrow therapeutic indices(c) Easy removal and termination(d) Drugs against peptic ulcerI have been asked this question in homework.My doubt stems from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

Which of the following drugs cannot be given as transdermal administra

1.	Which of the following drugs cannot be given as transdermal administration?(a) Drugs with very short half-lives(b) Drugs with narrow therapeutic indices(c) Easy removal and termination(d) Drugs against peptic ulcerI have been asked this question in homework.My doubt stems from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology
Answer» Right OPTION is (d) Drugs against peptic ulcer The explanation is: Transdermal DELIVERY SYSTEMS are topically administered medications. Drugs with very short half-live example nitro-glycerine are administered as transdermal patches. Drugs with narrow THERAPEUTIC indices can be safely administered through transdermal patches. Problems for ORAL administration are not seen here.

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