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Which of the following is false for monolithic devices?(a) The drug used for these devices has large therapeutic indices(b) There are three categories of matrix devices(c) 1st type has the drug dissolved in the polymer matrix(d) 2nd type has drug dispersedThis question was addressed to me during an interview.My question comes from Biopharmaceuticals topic in portion Biopharmaceuticals of Drug Biotechnology

Answer»

Right answer is (b) There are three categories of matrix devices

To ELABORATE: The DRUG used in these devices has a large therapeutic index. Such that overdosing does not PRECIPITATE toxic reactions. There are two categories of matrix devices ONE is where the drug is dissolved in the polymer matrix and the other is where the drug is dispersed. The polymer employed for the matrix system MAY be hydrophilic or lipophilic. These polymers include PVC, PVP, and polysaccharides.



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