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Which of the following oral controlled release system is shown in the picture?(a) Matrix system(b) Encapsulated system(c) Rigid matrix(d) Swellable matrixI got this question during an interview.Question is from Biopharmaceuticals in division Biopharmaceuticals of Drug Biotechnology

Answer»

Correct choice is (d) Swellable matrix

The best I can explain: Swellable matrix SYSTEMS are popular for sustaining the RELEASE of HIGHLY water soluble drugs. The materials for such matrices are generally hydrophilic gums such as GUAR gum, polyacrylamide etc. The drug and gum are granulated TOGETHER with a solvent and then are compressed into tablets.



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