1.

Which of the following would undergo Hoffmann reaction to give a primary amine ?

Answer»

`R-overset(O)overset("||")(C )-CL`
`RCONHCH_(3)`
`RCONH_(2)`
RCOOR

SOLUTION :When a primary amide is heated with an aqueous solution of KOH and `Br_(2)`, it gives a primary amine with one carbon atom less.
`RCONH_(2)+Br_(2)+4KOH overset(Delta)rarr RNH_(2)+2KBr+K_(2)CO_(3)+2H_(2)O`
This is known as Hoffmann DEGRADATION reaction.


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