1.

Which one of the following compounds is most reactive towards nucleophilic addition

Answer»

`CH_(3)CHO`
`PhCOCH_(3)`
`PhCOPh`
`CH_(3)COCH_(3)`

Solution :In nucleophilic addition reaction of carbonyl compounds order of reactivity is

The lower reactivity of ketones over aldehydes is due to `+I` effect of the alkyl group. The aromatic aldehydes and ketones are LESS reactive than their ALIPHATIC analogues. This is due to the `+R` effect of the benzene ring. From the above information, it is clear that INCREASING order of the nucleophilic addition reaction in the following compound will be, `PhCOPh lt PhCOCH_(3) lt CH_(3)COCH_(3) lt CH_(3)CHO`


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