Why are Enzymes active only over small range of pH?(a) Its enzymes property(b) Due to non-active site functional group charges(c) Due to the active site functional group charges(d) It prevents from structure destructionThe question was posed to me during an online interview.Question is taken from Methods of Immobilization topic in chapter Antibiotics & Enzyme Immobilization of Drug Biotechnology

Why are Enzymes active only over small range of pH?(a) Its enzymes pro

1.	Why are Enzymes active only over small range of pH?(a) Its enzymes property(b) Due to non-active site functional group charges(c) Due to the active site functional group charges(d) It prevents from structure destructionThe question was posed to me during an online interview.Question is taken from Methods of Immobilization topic in chapter Antibiotics & Enzyme Immobilization of Drug Biotechnology
Answer» Right answer is (c) Due to the active site FUNCTIONAL GROUP charges The best I can explain: Enzyme are active only over small range of PH due to the active site functional group charges (ionic FORM) and the three dimensional shape of enzyme are pH-dependent. Certain enzyme have ionic group on their active sites, and these ionic group must be in a suitable form (acid or BASE) to function.

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