InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 101. |
The introduction of t-DNA into plants involvesA. Allowing the plant roots to-stand in waterB. Infection of the plant by Agrobacterium tumefaeiensC. Altering the pH of the soil, then heat-shocking the plantsD. Exposing the plants to cold for a brief period |
| Answer» Correct Answer - B | |
| 102. |
Biosensors areA. enzymes used in industriesB. analytic devices used to monitor the product of biological process.C. used to detect abnormal toxins in bodyD. Both (b) and (c ) |
| Answer» Correct Answer - D | |
| 103. |
An improved variety of transgenic basmati riceA. dows not require chemical fertilisers and growth hormonesB. gives high yield and is rich in vitamin-AC. is completely resistant to all insect pests and diseases of paddyD. gives high yield but has no characteristic aroma |
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Answer» Correct Answer - B Goldnes rice (transgenic basmati rice) is a variety of Oryza sativa produced through genetic engineering to biosynthesise beta-carotene, a precursor of provitamin-A in the edible parts of rice the reasearch that led to golden rice was conducted with the goal of helping children who suffer from vitamin-A deficiency in poor countries. Golden rice has been bred to be especially disease-resistant, resulting in better crop yields. |
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| 104. |
Some of the characteristics of Bt-cotton are :A. long fibre and resistance to aphidsB. medium yield, long fibre and resistance to beetie pestsC. high yield and production of toxin protein crystals which kill dipteran pestsD. High yield and resistance to bollworms |
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Answer» Correct Answer - C Bacullus Thurringiensis forms crystals containing a toxic insecticidal protein. Bt toxin protein exists as inactive protein but once an insect ingests the inactive toxin, it is converted into an active form of toxin due to the alkaline pH of the gut, which solubulise the crystals. The activated toxin binds to the surface of midgur epithelial cells and creates pores that cause cells swelling and lysis and eventually cause death of the insect. specific Bt toxin genes were isolated from B. thuringiensis and incorporated into the sevaral plants suchh as cotton. The toxin is coded by a gene named cryi. there are a number of them, e.g. the proteins encoded by the genes cry I Ac and cry II Ab control the cotton bolloworms, that of cry I Ab control corn borers. |
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| 105. |
Some of the characteristics of Bt-cotton are :A. High yield and resistance to bollwormsB. Long fibre and resistance to aphidsC. Medium yield, long fibre and resistance to beetle pestsD. High yield and production of toxic protein crystals which kill dipteran pests |
| Answer» Correct Answer - A | |
| 106. |
Suggest any two possible tratments that can be given to a patient exhibiting adenosine deaminase deficiency. |
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Answer» (i) Enzyme repleacement therapy in which functional DNA is injected (ii) Bone nmarrow transplantation (iii) Gene therapy please see answer o fQ33 above (any two) |
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| 107. |
The process of separation and purification of expressed protein before marketing is calledA. Upstream processsingB. Downstream processingC. BioprocessingD. Postprodction processing |
| Answer» Correct Answer - B | |
| 108. |
Give example of a GM crop that can tolerate abiotic stress.A. Transgenic tomatoB. Bt-BrinjalC. Golden riceD. Pomato |
| Answer» Correct Answer - A | |
| 109. |
What is a GM crop ?A. Genetically Modifired cropB. Genic Mutated cropC. Genetically Mutated cropD. None of the above |
| Answer» Correct Answer - A | |
| 110. |
DNA or RNA segment tagged with a radioactive molecule is called :A. PlasmidB. VectorC. ProbeD. Clone |
| Answer» Correct Answer - C | |
| 111. |
Brazzein is produced byA. Pentadiplandra BrazzeanaB. Curcuma longaC. Azadirachta indicaD. None of the above |
| Answer» Correct Answer - A | |
| 112. |
Name the pest that destroys the cotton bolls. Explain the role of bacillus thuringensis in protecting the cotton drop against the pest to increase the yields . |
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Answer» (i) Bt cotton (Bacillus thuringinesis) produces proteins that kill insects like lepidoptaernans (tabcco budworm army worm ) coleopterand (bettles) and depterans (files mosquitoes) (ii) The torin is coded by a gene called cry which is of various types (iii) Bt tabacco was first culturd to kill hornworm (mancluca sexta ) |
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| 113. |
Explain how polymerase chian reaction (PCR) technique is helpful indetecting bacterial and viral disesases when symptoms of the disease are not yet visible ? Give two examples |
| Answer» Very low conventration of a bacteria or virus in human body can be detected by amplificaiton of their nucleic acid using the technique of polymerase chain reactoion (PCR) this method is applied to detech HIV in suspected AIDS patients and to detec mutatios in genes in suspected cancer patients | |
| 114. |
When DNA is transcribed into mRNA, usually the mRNA remains single - standarded but in some cases an RNA can be made that is complementary to the mRNA. This is called ………and its main funcion is to ……….. .A. antisense RNA, block gene expressionB. antisense RNA, amplify mRNAC. antisense RNA, enhance translationD. reverse transcription, enhance translation |
| Answer» Correct Answer - A | |
| 115. |
The complementary DNA of ADA was inserted inA. leucocytesB. lymphocytesC. liver cellsD. myeloma cells |
| Answer» Correct Answer - B | |
| 116. |
Match t he following and select the correct optionA. (i) (ii) (iii) (iv)B. (iv) (i) (iii) (ii)C. (iii) (ii) (iv) (i)D. (ii) (i) (iv) (iii) |
| Answer» Correct Answer - D | |
| 117. |
Pick the correct option from among those provided (i) biopoiracy is realted to which of the following (a) Traditional kanowledge ltbvrgt (b) Biomeolicules and regareding bioresources genses isolated form bioresouces (C ) bioresources (d) all of the above (ii) Which of hte follwing is used in biovour (a) a pathogen (b) toxin form a pathogen (C ) a delivery system for the bioweapon agen (d) all of the above (iii)Which of the following combinations of risk are associtated wiht genetically modified food? (iv) a trangence expression can achive whihc of the follwoing ? (a) prevent expression of a native gene (b) moidify an existing biosynthetic pathway (c ) produce a protein that itself produces the phenotype of interst (d) all of hte above |
| Answer» (i) (d),(ii)(d),(iii)(b),(iv)(d) | |
| 118. |
Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered? |
| Answer» When acive protein pharamaceuticals are taken orally the major problex that is encountered is their degradation by the nezymes and acidic medium to overcome these problesms the pharmaceuticval proteins must be coated by a film is r esistant to these degradating factores | |
| 119. |
Select the incorrect statementA. RNAi silencing takes place in all eukaryotic organisms as a method of celluiar defenseB. RNAi requires silencing of mRNA by binding of complementary ssDNA moleculeC. Complementary nucleic acid could be from mobile genetic elements (transposons)D. Ti plasmid with nematode specific genes have been used in RNAi |
| Answer» Correct Answer - B | |
| 120. |
First transgenic crop isA. cottonB. peaC. tobaccoD. flax |
| Answer» Correct Answer - A | |
| 121. |
Name the most commonly used enzymes in ELISA. |
| Answer» Peroxidase and alkaline phosphatase. | |
| 122. |
Which Bt crop is recently recommended for cultivation in India?A. CottonB. WheatC. SoybeanD. Rice |
| Answer» Correct Answer - C | |
| 123. |
Among the following, which chemical is used most commonly in cryopreservation as crypretectant ?A. DMSOB. GlycineC. GlycerolD. Mannitol |
| Answer» Correct Answer - A | |
| 124. |
Name the organism with which the discovery of RNAi is associated. |
| Answer» Caenorhabditis elegans | |
| 125. |
Biopatents are usually awarded for the discovery ofA. new cell linesB. new DNA sequencesC. GM strainsD. All of these |
| Answer» Correct Answer - D | |
| 126. |
The crops engineered for glyphosate are resistant/tolarant toA. HerbicidesB. FungiC. BacteriaD. Insects |
| Answer» Correct Answer - A | |
| 127. |
Do you thin animla organs will solve transplant problems ? |
| Answer» We are aware of the facts that trade of human organs is in full swing particularly kidney s are being sold at higher rates to orana borker violating a ban on such sale since 1994 organ donation agter deth is rare and most transplanted or ans are coming formf poor peole selling hem ofr cash the only way out is to develop this regard scientists have alrady creasted a huan sheep chimera which has the body of a sheep and half human organs the time is not far away when animals organs will solve transplant problems | |
| 128. |
How do the improvement of crop plants through gneentic engineering more advantageous than conventional breeeding ? |
| Answer» Plant breeding through genetic engineering make it possible to inset a specific gene or genes into plats throgh conventional breeding however it is not possible this is because gen are usually linked and if the disirable gene is linke with undesirble gene it is often not psosible to separte them and transfer only the disired charactermorevere conventional breding take too much time and possible onl in case of interspeices or iteraspeices crosses sometimes even interpeics crosses are not possible on the half humanorgans the time is not far away when animlas organs will solve transplant problems | |
| 129. |
Genetically engineered human insulin is called |
| Answer» Correct Answer - Humulin | |
| 130. |
Name the primary steroid which gives rise to male and female sex hormones |
| Answer» Correct Answer - Cholesterol | |
| 131. |
Human gene therapy requiresA. gene isolationB. introduction of DNA into target cellsC. inclusion of promoter sequenceD. All of the above |
| Answer» Correct Answer - D | |
| 132. |
Give the full form of ELISA which disease can be detected using it ? |
| Answer» Enzyme linked immuno sorbent asay it is used for the detction of (HIV) AIDS disease | |
| 133. |
A : Biofortified crops such as golden rice are helpful in overcoming the problem of night blindness in developing nations. R : It has enhanced nutritional content of vitamin A.A. If both Assertion & Reason are true and the reason is the correct explanation of the assertion, then mark (1 )B. If both Assertion & Reason are true but the reason is not the correct explanation of the assertion, then mark (2).C. If Assertion is true statement but Reason is false, then mark (3).D. If both Assertion and Reason are false statements, then mark (4). |
| Answer» Correct Answer - A | |
| 134. |
Discuss the advantages of GMO. |
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Answer» Advantages of GMO are (i) GMO food crops have shorter growing cycles, greater resistance to both insects and diseases, higher yields and higher nutritional value . (ii) GMO animals have increased production and nutritive values e.g., GM, cows may produce more milk. (iii) The world health organisation or WHO, claims that GMO plants and animals m ay allow food prices to drop as food sources become more abundan t. |
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| 135. |
Suggest some conventional method used evaluation for detection of diseased state. |
| Answer» Urine and serum analysis. | |
| 136. |
The first clinical gene therapy was given to a girl with which enzyme deficiency? |
| Answer» Adenosine dearninase | |
| 137. |
hGH extracted form dead human may result into gentic disease known asA. severe combined immuno deficiency diseaseB. pituitary dwarfismC. creutzfeldt jacobD. cystic fibrosis |
| Answer» Correct Answer - C | |
| 138. |
Match the following Columns. `{:(,"Column I",,,"Column II"),(A., "Virus resistance",,1.,"2, 4 - D"),(B.,"Somatic hybridisation",,2.,"Coat protein gene"),(C.,"Callus culture",,3.,"PEG"),(D.,"Vinagar",,4.,"cry gene"),(E.,"Insect resistance",,5.,"Fermentation"):}`A. `{:(A,,B,,C,,D,,E),(3,,2,,1,,4,,5):}`B. `{:(A,,B,,C,,D,,E),(5,,4,,2,,3,,1):} `C. `{:(A,,B,,C,,D,,E), (2,,3,,1,,5,,4):} `D. `{:(A,,B,,C,,D,,E),(1,,2,,3,,4,,5):} ` |
| Answer» Correct Answer - C | |
| 139. |
To make AAT extracted the AAT gene was coupled to a promoter for proteinA. globolinB. ` alpha ` - lactoglobulinC. ` beta ` - lactoglobulinD. None of these |
| Answer» Correct Answer - C | |
| 140. |
Which of the following is the first sheep to produce milk with AAT ?A. DollyB. MollyC. NooriD. Tracy |
| Answer» Correct Answer - D | |
| 141. |
The first clinical gene therapy was done for the treatment ofA. AIDSB. CancerC. Cystic firbosisD. SCID (server combined immuno deficeincy resutling form deficiency of ADA) |
| Answer» Correct Answer - D | |
| 142. |
The first clinical gene therapy was done for the treatment ofA. AIDSB. cancerC. cystic fibrosisD. SCID |
| Answer» Correct Answer - D | |
| 143. |
The first clinical gene therapy was given in the yearA. 1990B. 1992C. 1972D. 2001 |
| Answer» Correct Answer - A | |
| 144. |
The first clinical gene therapy was given for treating :A. diabetes mellitusB. chickenpoxC. rheumatoid arthritisD. adenosine deaminase deficiency |
| Answer» Correct Answer - D | |
| 145. |
Which of the following is a transgenic plantA. Flavr savrB. Meloidogyne incognitaC. Caenorhabditis elegansD. Oryza sativa |
| Answer» Correct Answer - A | |
| 146. |
What is legally wrong in the us patent law? |
| Answer» It doesnot recongnize technologies and methods in use inother countries as prior art | |
| 147. |
Select the wrong statement .A. Human insulin is being commercially produced from a transgenic species of Escherichia coliB. Genetically modified Bacillu huringiensis is used as biopesticide on commercialC. Human protein, `alpha ` - 1 antitrypsin, is used to treat emphysemaD. Bt toxin genes cry IAc control corn borer |
| Answer» Correct Answer - B | |
| 148. |
An alga which can be employed as food for humna being isA. ultohrixB. chlorellaC. spirogyraD. palasiphema |
| Answer» Correct Answer - B | |
| 149. |
The clot formation can be prevented by treatmet with ______ in gene therapy:A. DNAaseB. recombinant vaccineC. TPAD. TGF-B |
| Answer» Correct Answer - C | |
| 150. |
Which one of the following is now being commercially produced by biotechnological procedures?A. NicatineB. MorphineC. QuinineD. Insulin |
| Answer» Correct Answer - D | |