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1.

Asprin is obtained by the reacation of `(CH^(3)CO)^(2)O withA. benzoic acidB. salicylin acidC. phenolD. cresol

Answer» Correct Answer - B
2.

What are antimicrobials?

Answer» Antimicrobials:The chemical substance which destroy or prevent the development(or) inhibit the pathogenic action of microbes such as bacteria,fungi,virus are called antimicrobials E.g:lysozyme,Lactic acid etc.,Different types of anti microbial drugs are antibiotics, antiseptics,disinfectants.
3.

Which type of drugs come under anti-microbial drugs?A. Antiseptics, antibiotics, disinfectantsB. Tranquilizers, analgesics, antisepticsC. Tranquilizers, antiseptics, antifertilityD. Antiseptics, antacids, antihistamine

Answer» Correct Answer - A
Antiseptics anitibotics and disinfectants are antimicrobial drugs which are used to check or cure diseases caused by microbes or microorganis.
4.

Describe briefly the therapeutic action of different classes of drugs.

Answer» The therapeutic action of different classes of drugs discussed below.
Antacids:Chemical that remove the excess of acid in the stomach and maintain the pH to normal level are antacids
E.g:Omerazole,Lansoprozote etc.
Antihistamines:Chemicals that prevent the interaction of histamines with receptors of the stomach wall thus producing less amount of acid are anti hastamibnes
E.g:Dimetapp,terfenadine(seldane).
Tranquilizers:THe drugs which are used in the management (Or) treatment of psychoes and neuroses are called tranquilizers
E.g:Luminal,seconal,Barbituric acid etc.Barbiturates:Derivatives or barbituric acid which functions as important class of tranquilizers are called barbiturates E.g:Veronal,Amytal etc.,
Analgesis:These are to reduce to totally abolish pain without causing impairment of consciousness,mental confusion,incoordination,paralysis,disturbances of nervous system etc.Analgesics are classified as
i)Naritic analgesis:These are most potent and clinically useful agents causing depression of central nervous system and at the same time act as strong analgesics.
E.g:Morphine,codeine etc.Antimicrobials:The chemical substances which destroy (or) prevent the development (or)inhibit the pathogenic action of microbes such as bacteria,fungi,virus are called antimicrobials.E.g,:Lysozyme,Lactic acid etc.,
Antibiotics:The chemical substances produced by micro organisms and inhibit the growth or destroy microorganisms are called antibiotics.
(or)
The substance produced totally or partly by chemical synthesis in low concentration inhibits the growth (or) destroy microorganism by chemical synthesis in low concentration inhibits the growth (or) destroy microorganism by intervening in their metabolic process are called antibiotics.E.g:Penicillin chloramphenicol etc.
Antiseptics:The chemical, compounds that kill (or) prevent the growth of micro organism are called antoseptics.Antiseptics are the chemical substance apllied on the living tissues such as wounds,cuts ulcers and diseased skin surfaces.
Disinfectants:The chemical compounds used for killing (or) preventing the growth of microorganism are called disinfectants.
These are apllied to inanimate object like floors,drainage systems etc.ltbergt E.g: i) 4% aqueous of formaldehyde called formalin is a disinfectant
ii)0.3 ppm chlorine aqueous solution is disinfectant.
iii)`SO_(2)`in very low concentration is disinfectant.
Antifertility drugs:THjese are birth control pills and contains a mixture of synthetic estrogen and progesteron derivatives E.g:Norethindrone,Enthylestradiol(Novestrol).
5.

Passage 2 Antibiotics are the chemical substances which are produced by microorganisms like bacteria, fungi and moulds. Antibiotics can inhibit the growth or even destroy other microorganisms. Now-a-days, synthetic antibiotics are also available. The first successful antibiotic produced was penicillin. The antibiotics may be either bacteriocidal (kills the organism in the body) or bacteriostatic (inhibits the growth of organism). Ampicillin and amoxycillin are modified antibiotics. Broad spectrum antibiotics are effective against several types of harmful microorganisms. Answer the following questions : 1.Chloramphenicol is :A. antipyreticB. broad spectrum antibioticC. azo dyeD. tranquillzer

Answer» Correct Answer - B
6.

A compound X is used as antiseptic in 0.2% solution and as a disinfectant in 1% solution. Which of the following is X ?A. phenolB. soframyclnC. benzilD. iodoform

Answer» Correct Answer - A
7.

Assertion : 0.2 per cent solution of phenol is an antiseptic while its one percent solution is disinfectant. Reason : Antiseptics are also called disinfectant .A. If both assertion and reason are true and reason is the correct explanation of assertion .B. If both assertion and reason are true but reason is not the correct explanation of assertion .C. If assertion is true but reason is false.D. If both assertion and reason are false.

Answer» Correct Answer - C
Antiseptics are applied to the living tissues such as wounds and cuts whereas disinfectants are applied to inanimate objects such as floors, drainage systems ,etc .
8.

Write notes on antispeptics and sisinfectants.

Answer» Antiseptics:The chemical compounds that kill (or) prevent the growth of micro organism are called anti0septics.Antiseptics are the chemical substance apllied on the living tissues such as wounds,cuts,ulcers and diseased skin surfaces.E.g.:Dettol,Bithional etc.
Phenol is used as antiseptic as well as disinfectant.0.2% phenol is antispetic dettol(Antiseptic) is a mixture of chlorxylenol and terpineol.Tinture of iodine(antiseptic)Is a mixture of chloroxylenol and terpineiol.Tincture of iodine (antiseptic)is a mixture of 2-3% Iodine solution in alcholol-water.Disinfectants:The chemical compounds used for killing (or) preventing the growth of microorganism are called disinfectants.
i)These are apllied to inanimate object like floors,drainage system etc...E.g:4% aqueous solution of formaldehyde called formalin is a disinfectant.
ii)0.3 ppm chlorine aqueus solution is disinfectant.
iii)`SO_(2)` in very low concentration is disinfection phenol is used as antiseptic as well as disinfectant.1% phenol is disinfectant.
9.

What are different type of microbial drugs?Give one example for each.

Answer» antimicrobials:The chemical substances which destroy or prevent the development (or) inhibit the pathogenic acgtion of microbes such as bacteria fungi,virus are called antimicrobials E.g:Lysozyme ,Lactic acid etc.Different type of sntimicrobial drugs are antibiotics,disinfectants.
1)Antibiotics:The chemical substances produced by micro organisms and inhibit the growth or destroy microorganisms are called antibiotics.
(or) The substance produced totally or partly by chemical synthesis in low concentration inhibits the growth (or) destroy microorganims by intervening in their metabolic process are called antibiotic.
2) Antiseptics:The chemical compounds that kill (or) prevent the growth of micro organism are called antiseptics. Antiseptics are the chemical substances applied on the living tissues such as wounds,cuts,ulcers and Diseased skin surface.
10.

Use of chemicals for therapeutic effect is calledA. medicinesB. chemotherapyC. drug target interactionD. phototherapy

Answer» Correct Answer - B
11.

What are broad spectrum and narrow spectrum antibiotics?Give one example for each .

Answer» The range of bacteria (or) other micro organisms that are by a certain antibiotic is expressed as its spectrum of action.
Broad spectrum antibiotics:Antibiotics which kill (or) inhibit a wide range of gram-positive and gram-negative bacteria are called broad spectrum antibiotics.
Narrow spectrum antibiotics:Antibiotics which are effective mainly against gram-positive (or)gram-negative bacteria are called narrow spectrum antibiotics.
E.g.:Panicillin-G is a narrow spectrum antibiotic.
Limited soectrum antibiotics:Antibiotics which are effective mainly against a single organism (or) disease are called as limited spectrum antibiotics.
12.

Distinguish between antiseptic and disinfectant giving example of each.

Answer» Antiseptic - Applied to living tissues like cuts, wounds etc. These are generally dilute solutions e.g., Dettol, Soframicine etc.
Disinfectants- Applied to inanimate objects. These are generally concentrated solutions e.g., 1% Phenol, 0.2-0.4 % ppm in aqueous solution of chlorine.
13.

Write the characteristic properties of antibiotics.

Answer» Characristic properties of antibiotics:
1) Antibiotic drugs must be the produce of metabolism.
ii) Antibiotic drugs are effective in low concentration.
iii)Antibiotic drug retards the growth (or) survival of microorganism.
iv)Antibiotic should be a synthetic substance produced as a structural analogue of naturally occuring antibiotic.
v) Antibiotics have either cidal (Killing) effect (or) a static (inhibiting) effect on microbes Erythromycin,Tetracycline are Bacteriostatic.
14.

Which of the following is an anionic detergent-A. sodium stearateB. sodium lauryl sulphateC. cetyltrimethyl ammonium bromideD. glyceryl oleate

Answer» Correct Answer - B
15.

Which are broad spectrum antibiotics ?

Answer» Chloramphenicol, Ampicillin.
16.

What is meant by the term broad spectrum antibiotics?Explain.

Answer» The range of bacteria (or) other micro organisms that are effected by a certain antibiotic is expressed as its spectrum of action
Broad spectrum antibiotics:Antibiotics which skill (or) inhibit a wide range of gram-positive and gram-negative bacteria are called broad spectrum antibiotics.
17.

Which of the following are anionic detergents ?A. Sodium salts of sulphonated long chain alcoholB. Ester of stearic acid and polyethylene glycolC. Quaternary ammonium salt of amine with acetate ionD. Sodium salts of sulfonated long chain hydrocarbons

Answer» Correct Answer - A::D
18.

Give an example of an antihistamine drug.

Answer» Brompheniramine (Dimetapp).
19.

Which one of the following is employes as antihistamine ?A. ChloramphenicolB. NorothindroneC. Diphenylhy dramineD. Omeprazole

Answer» Correct Answer - C
20.

Assertion : Artificial sweeteners are added to the food to control the intake of calories. Reason: Most of the artificial sweeteners are inert and do not metabolise in the body.A. Assertion and reason both are correct statement but reason does not explain assertionB. Assertion and reason both are correct and reason explains the assertionC. Both assertion and reason are wrong statementD. Assertion is correct statement reason is wrong statement

Answer» Correct Answer - B
Reason is the correct explanation of assertion.
21.

Assertion (A) Artificial sweeteners are added to the food to control the intake of calories. Reason (R) Most of the artificial sweetnes are inert and do not metabolise in the body.A. Assertion and reason both are correct statements but reason does not explain assertion.B. Assertion and reason both are correct and reason explains the assertion.C. Both assertion and reason are wrong statements.D. Assertion is correct statement reason is wrong statement.

Answer» Correct Answer - B
Assertion and reason both are correct and reason explains the assertion. Artificial sweeternes are added to the food to control the intake of calories because most of the artificial sweeteners are inert and do not metabolies in the body.
22.

Which of the following is broad spectrum bactrericidal antibiotics?A. OlfaxacinB. ChloramphecnicolC. penicillinD. Tetracyclines

Answer» Correct Answer - A
23.

Which of the following inhibit the growth of microorgansim?A. TetracyaclineB. PecnicillinC. OlfaxacinD. Aminoglycosides

Answer» Correct Answer - A
24.

Which of the following is an anionic detergent ?A. Sodium stearateB. Sodium lauryl sulphateC. Cetyl trimethyl ammonium bromideD. Glyceryl oleate

Answer» Correct Answer - B
25.

The detergent used in tooth paste isA. cetyI trimethyI ammonium acetateB. stearyI trimethyI ammonium bromideC. sodium lauryI sulphateD. polyethylene glycol

Answer» Correct Answer - C
26.

Liquid washing detergent areA. anionic typesB. cationic typesC. non-ionic typesD. soap

Answer» Correct Answer - C
27.

Sodium dodecylbenzenesulphonate is a ______detergent.

Answer» Correct Answer - Anionic
28.

Chloramphenicol isA. bactericidal antibioticsB. bacteristatic antibioticsC. antispticD. antimalerial drugs

Answer» Correct Answer - B
29.

Assertion (A): Artificial sweeteners are added to the food to control the intake of calories. Reason (R) : Most of the artificial sweeteners are inert and do not metabolise in the body.A. (A) and (R ) both are correct statement but reason does not explain (A)B. (A) and (R ) both are correct statements and (R ) explains the (A)C. Both (A) and (R ) are wrong statementD. (A) is correct statement and (R ) is wrong statement

Answer» Correct Answer - B
30.

Chloramphenicol is :A. dyeB. tranquilizersC. borad spectrum antibioticsD. narrow spectrum antibiotics

Answer» Correct Answer - C
31.

Give an example of antihistamine drug.

Answer» Bromopheniramine (Dimeapp)
32.

Chloramphenicol is an-A. antihistaminieB. antiseptic & disinfectantC. antibiotic-broad spectrumD. antifertility drug

Answer» Correct Answer - C
33.

Which of the following compounds are used to cure mental depression-A. iproniazidB. phenelzineC. equanilD. salvarsan

Answer» Correct Answer - a,b,c
34.

Heroin is a derivative ofA. nicotinB. morphineC. cocainD. caffeine

Answer» Correct Answer - B
35.

Which of the following sweeteners has the lowest sweetness valueA. AlitameB. SucroloseC. SacchrinD. Aspartame

Answer» Correct Answer - D
Aspartame is 100 times sweeter than sources. Saccharin is 550 times sweeter then sources.
Sucrolose is 600 times sweeter than sources.
Alitame is 2000 times sweeter than sucrose.
36.

The role of phosphate in detergent powder is toA. provide whitness to the fabricB. remove `Ca^(2+)` and `Mg^(2+)` ions from the water that cause the hardness of waterC. Control pH level of the detergent water mixture.D. form solid detergent as phosphate less detergent are liquid in nature.

Answer» Correct Answer - C
Phospheates were added to commercial detergents for various purpose. They complexed the metal inos that contributed to water hardness and kept them dissolved, controlled acidity andinfluenced mecelle formation. The eutrophication in rivers an streams that recrive sewage. This is a condition (not reated to collies) in which an overgrowth of vegetation is casued by the high concentration of phosphours, a plant nutrient. This overgrowth and the subsequent decay of the dead plants lead to decreased dissolbed `O_(2)` in the water, which causes the gradual elimination of marine life.
37.

Heroin is a derivative of :A. morphineB. nicotineC. cocaineD. caffeine

Answer» Correct Answer - A
38.

Give one use of each of the following-(i) chloramphenicol, (ii) streptomycin, (iii) paracetamol, (iv) bithional

Answer» (i) In treating typhoid, (ii) In treating tuberculosis, (iii) In reducing arthiritic pain and fever, (iv) as an antiseptic
39.

Omeprazole is used to cure which disease of the human body?

Answer» Correct Answer - Hyperacidity
40.

Identify the compound case : A diacetyl derivative of morphine which is a powerful analgesic and extremely addictive.

Answer» Heroin, the diacetyl derivative of morphine, is a powerful analgesic and at the same time is extremely addictive.
41.

Give an example of a hormone and a neurotransmitter.

Answer» Adrenaline (hormone) and acetylcholine (neurotransmitter)
42.

Heroin is a derivative of morphine. Chemically, it isA. morphine monoacctateB. morphine dicateC. morphine triacetateD. morphine tetracetate

Answer» Correct Answer - B
Morphine `(C_(17) H_(19) NO_(3))` is the principal alkaloid of opium. It acts both as a base and as a phenol and reacts to form methylmorphine (codeine and diacelylmorphine (diamorphine or heroin).
43.

Naproxen is _______ analgesic

Answer» Correct Answer - non-narcotic
44.

Compound which is added to soap to impart antiseptic properties is `"………….."`A. sodium laurylsulphateB. sodium dodecylbenzenesulphonateC. rosinD. bithional

Answer» Correct Answer - D
Basically, all soaps are made by boiling fats or oils with suitable hydroxide Variations are made by adding different raw materials. Sodium laurysulphate and sodium dodecylbenzensulphonate are anionic detergents.
A gum rosin added to soap to make it lather well, Bithional is added to soaps to impart antiseptic properties to soap.
45.

What is added to a soap to impart antiseptic properties in it?

Answer» Correct Answer - Bithional
46.

`C^(14)H^(18)N^(2)O^(5)` isA. AspartameB. AlitameC. SucruloseD. Saccharin

Answer» Correct Answer - A
47.

Aspirin is chemically :A. acetyI salicylic acidB. containing acetoxy and cabxyI groupC. 2-acetoxy benzoic acidsD. all of these

Answer» Correct Answer - D
48.

Morphine or Heroin is a _______ analgesic

Answer» Correct Answer - narcotic
49.

Saccharin was discorved inA. 1780B. 1879C. 1980D. 1680

Answer» Correct Answer - B
50.

Give the chemical name of ibuprofen along with its use.

Answer» 2-(4-isobutylphenyl) propanoic acid and is a non-narcotic analgesic