

InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
51. |
Bacteria have ____________(a) 70S ribosomes(b) 60S ribosomes(c) 50S ribosomes(d) 80S ribosomesI had been asked this question during an online exam.This key question is from Protein Synthesis in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct option is (a) 70S ribosomes |
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52. |
Which position of a codon is said to wobble?(a) First(b) Second(c) Third(d) FourthI had been asked this question by my college professor while I was bunking the class.This intriguing question comes from The Genetic Code in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Right answer is (c) Third |
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53. |
How many t-RNAs are required to translate all 61 codons?(a) 31(b) 32(c) 30(d) 29The question was posed to me by my college director while I was bunking the class.The origin of the question is The Genetic Code in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct option is (b) 32 |
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54. |
Actinomycin D is an inhibitor of ____________(a) Transcription(b) Translation(c) Replication(d) None of the mentionedThis question was posed to me in homework.My question is based upon DNA-Dependent Synthesis of RNA in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct OPTION is (a) Transcription |
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55. |
Which of the following process occurs in regions where no large –scale sequence similarity is apparent?(a) Homologous genetic recombination(b) Site specific recombination(c) Non-homologous recombination(d) Replicative recombinationI have been asked this question in an online quiz.Origin of the question is DNA Recombination in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct ANSWER is (c) Non-homologous recombination |
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56. |
In which of the following cases the first base of anticodon pairs with three codons?(a) When the first base of anticodon is A or C(b) When the first base of anticodon is A or G(c) When the first base of anticodon is inosine(d) When the first base of anticodon is G or UThe question was posed to me in final exam.Asked question is from The Genetic Code topic in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The CORRECT OPTION is (c) When the first base of anticodon is INOSINE |
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57. |
Transcription is catalyzed by ____________(a) DNA-dependent RNA polymerases(b) RNA-dependent DNA polymerases(c) Reverse transcriptases(d) DNA ligasesThe question was asked in unit test.The origin of the question is DNA-Dependent Synthesis of RNA topic in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct ANSWER is (a) DNA-dependent RNA polymerases |
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58. |
Which of the following occurs between particular short sequences present on otherwise dissimilar parental molecules?(a) Homologous genetic recombination(b) Site specific recombination(c) Non-homologous recombination(d) Replicative recombinationI had been asked this question in an internship interview.I would like to ask this question from DNA Recombination topic in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct CHOICE is (b) Site specific RECOMBINATION |
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59. |
A point mutation that replaces a purine with another purine, or a pyrimidine with another pyramidine ____________(a) Nonsense mutation(b) Silent mutation(c) Transition mutation(d) TransversionI got this question during an interview for a job.My enquiry is from DNA Repair topic in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct answer is (c) Transition MUTATION |
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60. |
Which of the following process occurs between DNA molecules of very similar sequences?(a) Homologous genetic recombination(b) Site specific recombination(c) Non-homologous recombination(d) Replicative recombinationThe question was asked in final exam.Question is taken from DNA Recombination topic in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» | |
61. |
An alteration in a nucleotide sequence that changes a triplet coding for an amino acid into a termination codon is ____________(a) Nonsense mutation(b) Mutagenesis(c) Mutation(d) MutagenThe question was posed to me during an interview.My enquiry is from DNA Repair topic in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT choice is (a) Nonsense mutation Easiest explanation: Nonsense mutation (point mutation) results in a PREMATURE STOP CODON. |
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62. |
Which of the following reactions is required for proofreading during DNA replication by DNA polymerase III?(a) 5’ to 3’ exonuclease activity(b) 3’ to 5’ exonuclease activity(c) 3’ to 5’ endonuclease activity(d) 5’ to 3’ endonuclease activityThe question was asked in semester exam.Enquiry is from DNA Replication in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct choice is (b) 3’ to 5’ EXONUCLEASE ACTIVITY |
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63. |
In which of the following cases the first base of anticodon pairs with only one codon?(a) When the first base of anticodon is A or C(b) When the first base of anticodon is A or G(c) When the first base of anticodon is inosine(d) When the first base of anticodon is G or UI have been asked this question in an online interview.This intriguing question comes from The Genetic Code in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Right option is (a) When the FIRST base of anticodon is A or C |
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64. |
The coated pits are coated on their cytosolic side with a lattice of ____________(a) Clathrin(b) Lipoprotein(c) Glycoprotein(d) TransferrinI had been asked this question in an online interview.Enquiry is from Protein Targeting and Degradation in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT option is (a) Clathrin Best explanation: Clathrin is COATED on the CYTOSOLIC side of the coated PITS. |
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65. |
The initiation codon is ____________(a) AUG(b) UAA(c) UAG(d) UGAThis question was addressed to me during an internship interview.I need to ask this question from The Genetic Code in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT option is (a) AUG Easy explanation: UAA, UAG and UGA are termination CODONS. |
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66. |
Which type of homing is DNA-based?(a) Group I intron(b) Group II intron(c) Group III intron(d) Group IV intronThe question was asked in an interview for job.I want to ask this question from RNA-Dependent Synthesis of RNA and DNA topic in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct CHOICE is (a) GROUP I intron |
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67. |
Which is the first nucleic acid synthesizing enzyme discovered?(a) Polynucleotide phosphorylase(b) DNA polymerase(c) RNA polymerase(d) DNA ligaseI got this question in an interview for internship.My doubt stems from RNA Processing in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT choice is (a) Polynucleotide PHOSPHORYLASE The best explanation: Polynucleotide phosphorylase is the first nucleic acid SYNTHESIZING enzyme DISCOVERED. |
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68. |
What is the reaction in DNA replication catalyzed by DNA ligase?(a) Addition of new nucleotides to the leading strand(b) Addition of new nucleotide to the lagging strand(c) Formation of a phosphodiester bond between the 3’-OH of one Okazaki fragment and the 5’-phosphate of the next on the lagging strand(d) Base pairing of the template and the newly formed DNA strandI got this question in an interview for job.This interesting question is from DNA Replication in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct option is (c) Formation of a phosphodiester BOND between the 3’-OH of one OKAZAKI fragment and the 5’-phosphate of the NEXT on the lagging strand |
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69. |
How many amino acid residues are there in ubiquitin?(a) 72(b) 73(c) 75(d) 76This question was addressed to me by my school teacher while I was bunking the class.The doubt is from Protein Targeting and Degradation in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct choice is (d) 76 |
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70. |
Wobble hypothesis was first proposed by ____________(a) Nirenberg(b) Watson and Crick(c) Watson(d) CrickThis question was addressed to me in an interview for job.The question is from The Genetic Code in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct choice is (d) Crick |
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71. |
What is the role of sigma factor in bacterial RNA polymerase?(a) Catalyzing RNA synthesis(b) Positioning RNA polymerase correctly on the DNA template(c) Terminating RNA synthesis(d) Unwinding DNA templateI have been asked this question in an interview for internship.My doubt is from DNA-Dependent Synthesis of RNA in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The CORRECT choice is (b) Positioning RNA polymerase correctly on the DNA template |
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72. |
Repressors bind to ____________(a) Promoter(b) Enhancer(c) Operator(d) Hormone response elementThis question was addressed to me in quiz.I'd like to ask this question from DNA-Dependent Synthesis of RNA in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct answer is (C) OPERATOR |
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73. |
If the mutation has a negligible effect on the function of a gene, it is known as a ____________(a) Silent mutation(b) Frame shift mutation(c) Substitution mutation(d) Insertion mutationI had been asked this question by my college professor while I was bunking the class.Asked question is from DNA Repair in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct answer is (a) SILENT mutation |
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74. |
Which of the following does not code for an enzyme having both helicase and nuclease activity?(a) Rec-A(b) Rec-B(c) Rec-C(d) Rec-DThe question was asked in an internship interview.My question comes from DNA Recombination in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Right answer is (a) Rec-A |
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75. |
The genetic code translated the language of ____________(a) Proteins into that of RNA(b) Amino acids into that of RNA(c) RNA into that of proteins(d) RNA into that of DNAI got this question in my homework.My question is taken from The Genetic Code topic in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The CORRECT choice is (c) RNA into that of proteins |
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76. |
Which of the following inhibits initiation at higher concentrations?(a) Chloramphenicol(b) Streptomycin(c) Diphtheria toxin(d) RicinThis question was posed to me in semester exam.This interesting question is from Protein Synthesis in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The CORRECT choice is (B) Streptomycin |
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77. |
Which of the following are not DNA viruses?(a) Hepatitis B virus(b) Influenza A virus(c) CMV virus(d) ParvovirusThis question was addressed to me by my college professor while I was bunking the class.The above asked question is from RNA-Dependent Synthesis of RNA and DNA in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Right ANSWER is (B) Influenza A virus |
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78. |
Which of the following is true about RNA synthesis?(a) Synthesis of RNA is always in the 5’ to 3’ direction(b) RNA polymerase requires a primer for initiating transcription(c) U is inserted opposite T in transcription(d) New nucleotides are added on the 2’-OH of the ribose sugarThe question was asked during an online interview.The above asked question is from DNA-Dependent Synthesis of RNA topic in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct answer is (a) SYNTHESIS of RNA is ALWAYS in the 5’ to 3’ direction |
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79. |
Semi-conservative DNA replication was first demonstrated in ____________(a) Drosophila melanogaster(b) Escherichia coli(c) Streptococcus pneumonae(d) Drosophila melanogasterThe question was posed to me in a job interview.My question is based upon DNA Replication topic in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct OPTION is (a) DROSOPHILA melanogaster |
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80. |
Which of the following mechanisms will remove uracil and incorporate the correct base?(a) Direct repair(b) Base excision repair(c) Mismatch repair(d) Nucleotide excision repairI have been asked this question during an internship interview.Question is taken from DNA Repair topic in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct CHOICE is (b) Base excision repair |
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81. |
What is DNA replication?(a) Conservative(b) Non-conservative(c) Semi-conservative(d) None of the mentionedThis question was addressed to me in an interview.My query is from DNA Replication in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct ANSWER is (c) Semi-conservative |
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82. |
The antibiotic aided in elucidating the steps of protein glycosylation is ____________(a) Streptomycin(b) Tunicamycin(c) Penicillin(d) CrocinThe question was asked during an interview.This key question is from Protein Targeting and Degradation topic in section DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct ANSWER is (B) Tunicamycin |
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83. |
Which of the following is RNA-dependent RNA polymerase?(a) Reverse transcriptase(b) RNA polymerase I(c) RNA polymerase II(d) RNA replicaseI had been asked this question in unit test.Origin of the question is RNA-Dependent Synthesis of RNA and DNA topic in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct choice is (d) RNA replicase |
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84. |
Which is an example of RNA-dependent DNA polymerase?(a) Reverse transcriptase(b) DNA ligase(c) RNA polymerase I(d) RNA polymerase IIThis question was posed to me in homework.Question is from RNA-Dependent Synthesis of RNA and DNA topic in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct answer is (a) REVERSE transcriptase |
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85. |
The sequences of the recombination sites recognized by site-specific recombinases are ____________(a) Partially asymmetric(b) Partially symmetric(c) Symmetric(d) PalindromicI have been asked this question in an interview.The doubt is from DNA Recombination topic in division DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT choice is (a) Partially ASYMMETRIC The explanation: The sequences of the recombination sites recognized by site-specific recombinases are partially asymmetric (non-palindromic). |
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86. |
RNA primer is removed from the Okazaki fragment by ____________(a) DNA polymerase I(b) DNA polymerase II(c) DNA polymerase III(d) RNA polymeraseI have been asked this question in exam.Query is from DNA-Dependent Synthesis of RNA topic in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» CORRECT answer is (a) DNA polymerase I To ELABORATE: DNA polymerase I remove RNA PRIMER from Okazaki FRAGMENT. |
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87. |
What are the two subassemblies of 26S proteasome?(a) 20S core particle and 19S regulatory particle(b) 20S regulatory particle and 19S core particle(c) 18S core particle and 19S regulatory particle(d) 20S core particle and 18S regulatory particleThis question was posed to me in class test.Enquiry is from Protein Targeting and Degradation in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Correct CHOICE is (a) 20S core particle and 19S REGULATORY particle |
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88. |
What is the role of small nuclear RNAs in protein synthesis?(a) It translates genetic code to a specific amino acid(b) It modifies mRNA molecules prior to protein synthesis(c) It provides a genetic blueprint for the protein(d) It catalyzes the processI have been asked this question in homework.This interesting question is from Protein Synthesis in portion DNA, RNA and Protein Metabolism of Biochemistry |
Answer» Right option is (B) It modifies MRNA MOLECULES prior to protein synthesis |
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89. |
Which of the following contains only the sequences required for transposition and the genes for proteins that promote the process?(a) Insertion sequences(b) Complex transposons(c) Transposons(d) ChromosomesI have been asked this question in an international level competition.I'd like to ask this question from DNA Recombination topic in chapter DNA, RNA and Protein Metabolism of Biochemistry |
Answer» The correct choice is (a) Insertion sequences |
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