InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Probes used in DNA finger-printing initiallyA. 19 base long oligonucleotideB. single stranded RNAC. minisatelliteD. all of the above |
| Answer» Correct Answer - A | |
| 2. |
The colonies of recombinant bacteria appear white in contrast to blue colonies of non-recombinant bacteria because ofA. Insertional inactivation of alpha-galactosidase in non-recombinant bacteriaB. Insertional inactivation of alpha-galactosidase in recombinant bacteriaC. Inactivation of glycosidase enzyme in recombinant bacteriaD. Non-recombinant bacteria containing beta-galactosidase |
| Answer» Correct Answer - B | |
| 3. |
If an inheritable mutation is observed in a population at high frequency it is reffered to asA. LinkageB. DNA polymorphismC. Sequence annotationD. Expressed sequence tag |
| Answer» Correct Answer - B | |
| 4. |
Lactose (Lac) operon is regulated by :A. Lac repressor onlyB. Lac repressor and CAP-cGMP complexC. Lac repressor and CAP-cAMP complexD. CAP-cAMP and CAP-c-GMP complex |
| Answer» Correct Answer - C | |
| 5. |
According to the lac operon concept, which functional unit of the bacterial genetic material is responsible for suppressing the activity of the operator gene in the absence of lactose ?A. Promoter geneB. Regulator geneC. Structural geneD. Repressor protein |
| Answer» Correct Answer - B | |
| 6. |
What does 'lac' refer to in what we call the lac operon ?A. catabolic induction allosteric inhibitionB. LactoseC. LactaseD. Lac insect |
| Answer» Correct Answer - A | |
| 7. |
Genes that are involved in turning on or off the transcription of set of structural genes are called Or Functioning of structural genes is controlled byA. operator geneB. regulator genesC. reduntant genesD. polymorphic genes |
| Answer» Correct Answer - B | |
| 8. |
In operon concept, the operator gene combines with :A. regulator gene to switch off structural gene transcriptionB. inducer to switch off structural gene transcriptionC. regulator protein to switch on structural gene transcriptionD. regulator protein to switch off structural gene transcription |
| Answer» Correct Answer - D | |
| 9. |
Functioning of structural gene is controlled by:A. operatorB. ligaseC. promoterD. regulator gene |
| Answer» Correct Answer - A | |
| 10. |
DNA sequences that code for protein are known as :A. intronsB. exonsC. control regionsD. intervening sequences |
| Answer» Correct Answer - B | |
| 11. |
The lac operon consists of :A. four regulatory genes onlyB. one regulatory gene and three structural genesC. two regulatory gene and two structural genesD. three regulatory gene and three structural genes |
| Answer» Correct Answer - D | |
| 12. |
Which type of prokaryotic cell would be more successful as judged by its growth potential ?A. One that is able to express all its genes all the timeB. One that expresses some of its genes some of the timeC. One that is unable to express any of its genes any of the timeD. One that divides only when all types of amino acids and sugars are present in the medium |
| Answer» Correct Answer - B | |
| 13. |
Genes that are continuously functional and whose regulations at tissue level as in kidney, liver are known as :A. luxury geneB. gene battery modelC. house keeping geneD. mild genes (functional genes) |
| Answer» Correct Answer - C | |
| 14. |
Identify the molecule shown below : A. m-RNAB. t-RNAC. r-RNAD. hn-RNA |
| Answer» Correct Answer - B | |
| 15. |
Consider the following statements with respect to translation. A. Translation refers to the process of polymerisation of ribonucleotides. B. The site of translation (protein synthesis) is ribosomes. (D) An m-RNA also has untranslated regions (UTR) that are not translated. Of the above statements :A. B and D are correctB. A and B are correctC. A and C are correctD. A and D are correct |
| Answer» Correct Answer - A | |
| 16. |
DNA fingerprinting refers toA. Molecular analysis of profiles of DNA samplesB. Analysis of DNA samples using imprinting devicesC. Techniques used for identification of fingerprints of individualsD. Techniques used for molecular analysis of different specimens of DNA |
| Answer» Correct Answer - A | |
| 17. |
The lac operon is an example of :A. arabinose operonB. inducible operonC. repressible operonD. overlapping genes |
| Answer» Correct Answer - B | |
| 18. |
Diagrammatic view of a dinucleotide is given below. Identify A,B and D by selecting the correct option : A. `{:(A,B,D),("Nitrogenous base","Pentose sugar","Phosphate"):}`B. `{:(A,B,D),("Phosphate","Nitrogenous base","Pentose sugar"):}`C. `{:(A,B,D),("Pentose sugar","Phosphate","Nitrogenous base"):}`D. `{:(A,B,D),("Phosphate","Pentose sugar","Nitrogenous base"):}` |
| Answer» Correct Answer - D | |
| 19. |
Both deoxyribose and ribose belong to a class of sugars calledA. triosesB. pentosesC. hexosesD. polysaccharides |
| Answer» Correct Answer - B | |
| 20. |
Schematic structure of a transcription uit is given below. Select the correct option : A. A - Promoter, B - Structural gene, C - Terminator, D - Coding strandB. A - Terminator, B - Structural gene, C - Promoter, D - Coding strandC. A -Structural gene, B - Promoter, C - Terminator, D - Coding strandD. A -Promoter, B - Structural gene, C - Coding strand, D - Terminator |
| Answer» Correct Answer - A | |
| 21. |
Which one of the following statements is wrong ?A. RNA was the first genetic material.B. Nucleosomes constitute the repeating unit of a structure in the nucleus called chromatin.C. A typical nucleosome sontains 250 bp of DNA helix.D. Watson and Crick proposed double helix model for the structure of DNA in 1953. |
| Answer» Correct Answer - C | |
| 22. |
Choose the wrong statement :A. VNTR belong to a class of mini-satellite DNAB. Satellite DNA normally do not code for proteinsC. DNA sequencing work on the principle developed by Frederick SangerD. DNA fingerprinting involves identifying similarities in repetitive DNA |
| Answer» Correct Answer - D | |
| 23. |
Which of the following techniques is useful in forensic science ?A. Genectic imprintingB. DNA footprintingC. DNA fingerprintingD. All of these |
| Answer» Correct Answer - C | |
| 24. |
Find the wrongly matched pair:A. Har Gobind Khorana - Synthesised RNA molecules chemicallyB. George Gamow - Codon is tripletC. Meselson and Stahl - Regulation of gene expressionD. Alec Jeffreys - DNA fingerprinting |
| Answer» Correct Answer - C | |
| 25. |
Which of the following takes place in DNA fingerprinting ?A. A positive identification can be madeB. Multiple restriction enzyme digests generate unique fragmentsC. The polymerase chain reaction amplifies fewer DNAD. The variability of repeated sequences between two restriction sites is evaluated |
| Answer» Correct Answer - D | |
| 26. |
Which one of the following is wrongly matched ?A. Operon - Structrual genes, operator and promoterB. Transcription - Writing information from DNA to t-RNAC. Translation - Using information in m-RNA to make proteinD. Repressor protein - Binds to operator to stop enzyme synthesis |
| Answer» Correct Answer - B | |
| 27. |
Match column I with column II and choose the correct option. A. A-2, B-5, C-1, D-3B. A-3, B-4, C-2, D-1C. A-2, B-4, C-3, D-1D. A-1, B-5, C-4, D-2 |
| Answer» Correct Answer - C | |
| 28. |
Aminoacylation of t-RNA is essential for :A. splicingB. terminationC. replication of RNAD. formation of peptide bond |
| Answer» Correct Answer - D | |
| 29. |
When tryptophan is present :A. transcription of structural genes occursB. the repressor is able to bind to the operatorC. the repressor is unable to bind to the operatorD. both (b) and (c) are correct |
| Answer» Correct Answer - B | |
| 30. |
With regard to mature mRNA in eukaryotesA. Exons and introns do not appear in the mature RNA.B. Both exons and introns appear in the mature RNA.C. Exons appear but introns do not appear in the mature RNA.D. Introns apear but exons do not appear in the mature RNA. |
| Answer» Correct Answer - C | |
| 31. |
The regulatory genes are located :A. in front of the structural genesB. along with the structural genesC. at the end of the structural genesD. in the middle of the structural genes |
| Answer» Correct Answer - A | |
| 32. |
In operon concept, regulator gene functions as:A. inhibitorB. initiatorC. repressorD. regulator |
| Answer» Correct Answer - C | |
| 33. |
In operon model, regulator gene :A. prevents the movement of RNAB. stops the formation of r-RNAC. inactivates the substrateD. stops the transcription |
| Answer» Correct Answer - D | |
| 34. |
When lactose is present :A. the repressor is able to bind to the operatorB. the repressor is unable to bind to the operatorC. the repressor of lac Y, lac Z and lac A genes occursD. both (b) and (c) are correct |
| Answer» Correct Answer - D | |
| 35. |
Which one of the following acts as an inducer in the regulatory of operon model ?A. GlucoseB. LactoseC. SucroseD. Fructose |
| Answer» Correct Answer - B | |
| 36. |
In Escherichia coli, lac operon is induced by :A. LactoseB. I-geneC. Promoter geneD. `beta`-galactosidase |
| Answer» Correct Answer - A | |
| 37. |
How many structural genes are present in the tryptophan operon of Escherichia coli ?A. ThreeB. FiveC. SevenD. One only |
| Answer» Correct Answer - B | |
| 38. |
This is not produced by E.coli in the lactose medium :A. `beta`-galactosidaseB. lactose permeaseC. lactose dehydrogenaseD. thiogalactoside transacetylase |
| Answer» Correct Answer - C | |
| 39. |
In regulation of gene expression in prokaryotes : A. Lactose acts as an the suppressor for gene expression B. Tryptophan acts as the inducer for gene expression C. Regulator gene is the one that produces the repressor moleculeA. A alone correctB. B alone correctC. C alone correctD. B and A are correct |
| Answer» Correct Answer - C | |
| 40. |
The segment of a DNA molecule determining the amino acid sequence of a protein, is known as :A. operator geneB. regulator geneC. structural geneD. modifier gene |
|
Answer» Correct Answer - C Structural gene determines the primary structure of a protein by genetic transcription and translation. |
|
| 41. |
DNA fragments result when........cut DNA molecules at specific sites.A. RFLPsB. DNA probesC. DNA polymeraseD. Restriction enzymes |
| Answer» Correct Answer - D | |
| 42. |
When lactose is added to the culture of E. coli, a few of its molecules get into the cells with help of :A. lactaseB. permeaseC. galactosidaseD. transacetylase |
| Answer» Correct Answer - B | |
| 43. |
The protein required for the transport of galactose across the cell membrane in E.coli is :A. allolactaseB. transcriptaseC. `beta`-galactosidaseD. galactose permease |
| Answer» Correct Answer - D | |
| 44. |
Which one of the following is not an application of DNA fingerprinting ?A. Therapy for curing SCIDB. Solving paternity casesC. Identifying gene mutationD. Solving immigration cases |
| Answer» Correct Answer - A | |
| 45. |
Human genome project was discoverd byA. Francis Collins and RoderickB. Paul Berg and WollmanC. Watson and CrickD. Beadle and Tatum |
| Answer» Correct Answer - A | |
| 46. |
Human Genome Project was officially started in :A. 1989B. 1990C. 1985D. 1993 |
| Answer» Correct Answer - B | |
| 47. |
Molecular basis of organ differentiation depends on the modulation in transcription byA. RibosomeB. AnticodonC. RNA polymeraseD. Transcription factor |
| Answer» Correct Answer - D | |
| 48. |
How are RFLPs detected ?A. By amplifying the DNA using PCRB. By doing standard Mendelian crossC. By observing DNA of different lengths on a gelD. By looking at the chromosome in the microscope |
| Answer» Correct Answer - C | |
| 49. |
The basis of DNA fingerprinting is :A. availability of cloned DNAB. knowledge of human karyotypeC. phenotypic difference between individualsD. occurrence of RFLP (restriction fragment length polymorphism) |
| Answer» Correct Answer - D | |
| 50. |
RFLPs are distinguished using which technique ?A. CloningB. Colony blotC. Southern blotD. Sequencing |
| Answer» Correct Answer - C | |