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This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following is energy independent?(a) Active transport(b) Primary active transport(c) Secondary active transport(d) Passive transportThis question was posed to me during an online exam.The origin of the question is Solute Transport across Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer» RIGHT ANSWER is (d) PASSIVE transport

To explain: Active transport is ATP DEPENDENT.
2.

Which of the following is an example of heterodimeric protein?(a) Integrin(b) Antibodies(c) Receptor tyrosine kinase(d) G-protein coupled receptorI have been asked this question by my school teacher while I was bunking the class.The question is from Membrane Dynamics topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT choice is (a) Integrin

Explanation: Antibodies, RECEPTOR tyrosine kinase and G-protein COUPLED receptor are homodimeric.
3.

Trans bilayer diffusion is also called ____________(a) Facilitated diffusion(b) Lateral diffusion(c) Flip flop(d) Simple diffusionI had been asked this question in quiz.I need to ask this question from Membrane Dynamics in section Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT answer is (c) FLIP FLOP

Easiest EXPLANATION: Trans bilayer diffusion is also called “Flip flop”.
4.

Which of the following arrangement based on the increasing order of motion is correct?(a) Uncatalysed transverse motion, transverse diffusion catalyzed by flippase, uncatalysed lateral diffusion(b) Uncatalysed lateral diffusion, uncatalysed transverse motion, transverse diffusion catalyzed by flippase(c) Uncatalysed transverse motion, uncatalysed lateral diffusion, transverse diffusion catalyzed by flippase(d) Transverse diffusion catalyzed by flippase, uncatalysed lateral diffusion, uncatalysed transverse motionThe question was asked in a job interview.Question is from Membrane Dynamics in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct option is (a) UNCATALYSED transverse MOTION, transverse diffusion catalyzed by flippase, uncatalysed lateral diffusion

Best explanation: Uncatalysed transverse motion (slow), transverse diffusion catalyzed by flippase (FAST), uncatalysed lateral diffusion (very fast).

5.

Which of the following has high lipid content?(a) Myelin sheath(b) Plasma membrane(c) Inner mitochondrial membrane(d) Outer mitochondrial membraneI have been asked this question by my school principal while I was bunking the class.Asked question is from The Composition and Architecture of Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right choice is (a) Myelin sheath

Easy EXPLANATION: Myelin sheath relatively CONTAINS HIGH LIPID CONTENT.

6.

Which of the following membranes contain low cholesterol and high cardiolipin?(a) Myelin sheath(b) Plasma membrane(c) Inner mitochondrial membrane of hepatocyte(d) Cell wallThis question was addressed to me in an interview.This is a very interesting question from The Composition and Architecture of Membranes in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right answer is (c) INNER mitochondrial MEMBRANE of hepatocyte

Easy explanation: Inner mitochondrial membrane contains LOW cholesterol and HIGH cardiolipin.

Plasma membrane has high cholesterol and low cardiolipin.

7.

In which type of chromatography, solvents of increasing polarity are passed through a column of silica gel?(a) High performance liquid chromatography(b) Thin layer chromatography(c) Adsorption chromatography(d) Gas-liquid chromatographyI got this question during an interview for a job.I want to ask this question from Working with Lipids in section Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct answer is (C) ADSORPTION CHROMATOGRAPHY

For explanation: During adsorption chromatography, through a column of silica gel solvents of increasing POLARITY are passed.

8.

The backbone of phospholipids is __________(a) L-glycerol 1-phosphate(b) L-glycerol 3-phosphate(c) D-glycerol 3-phosphate(d) sn-glycerol 1-phosphateThis question was posed to me by my school teacher while I was bunking the class.This is a very interesting question from Structural Lipids in Membranes in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT OPTION is (B) L-glycerol 3-phosphate

The explanation: L-glycerol 3-phosphate or D-glycerol 1-phosphate or sn-glycerol 3-phosphate is the backbone of PHOSPHOLIPIDS.

9.

Which of the following group of membrane lipids predominate in plant cells?(a) Galactolipids(b) Sphingolipids(c) Glycerophospholipids(d) Archaebacterial ether lipidsThis question was addressed to me by my school teacher while I was bunking the class.My doubt is from Structural Lipids in Membranes topic in section Lipids, Biological Membranes and Transport of Biochemistry

Answer» RIGHT choice is (a) GALACTOLIPIDS

For EXPLANATION: Galactolipids are the LIPIDS predominant in the chloroplasts of PLANTS.
10.

Which of the following is a storage form of lipid?(a) Glycolipid(b) Phospholipid(c) Sufolipid(d) Triacyl glycerolThis question was posed to me during an online interview.This is a very interesting question from Storage Lipids topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right CHOICE is (d) Triacyl GLYCEROL

To ELABORATE: Triacyl glycerol is the STORAGE FORM of lipids.

11.

Out of the following, cholesterol does not serve as a precursor for which compounds?(a) Vitamin D(b) Sex hormones(c) Bile salts(d) Bile pigmentsThe question was asked in quiz.I'm obligated to ask this question of Structural Lipids in Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct answer is (d) BILE pigments

Best explanation: CHOLESTEROL serves as a PRECURSOR for the BIOSYNTHESIS of steroid molecules, bile acids and VITAMIN D.

12.

Out of the following, which is not an essential amino acid?(a) Linolic acid(b) Linolenic acid(c) Arachidic acid(d) Arachidonic acidI got this question in an interview.Enquiry is from Storage Lipids in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT option is (c) Arachidic ACID

For explanation I would SAY: Arachidic acid is a non-essential amino acid.
13.

Erythrocyte glucose transporter is an example of ____________(a) Ion driven active transport(b) Facilitated diffusion(c) Active transport(d) Simple diffusionI have been asked this question in examination.My question comes from Solute Transport across Membranes topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT CHOICE is (b) FACILITATED diffusion

To elaborate: TRANSPORTATION is facilitated by carrier PROTEINS.
14.

In which of the following means of transport a cell expels large molecules out of it?(a) Phagocytosis(b) Exocytosis(c) Endocytosis(d) DiffusionThe question was posed to me during a job interview.Asked question is from Solute Transport across Membranes in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» RIGHT CHOICE is (b) Exocytosis

Easiest explanation: In exocytosis, a cell expels LARGE MOLECULES out of it.
15.

A platelet is able to play its role in the formation of blood clot when one of the glycerophospholipids in the plasma membrane moves into the outer leaflet.(a) Phosphatidylserine(b) Phosphatidylethanolamine(c) Phosphatidylinositol(d) PhosphatidylglycerolI had been asked this question in semester exam.This question is from The Composition and Architecture of Membranes in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right choice is (a) Phosphatidylserine

Easy explanation: Only when phosphatidylserine in the PLASMA membrane moves into the outer LEAFLET is a platelet able to play its role in the FORMATION of BLOOD clot.

16.

Which of the following is important in signal transduction triggered by hormones?(a) Phosphatidylinositol and its derivatives(b) Phosphatidylserine and its derivatives(c) Phosphatidylglycerol and its derivatives(d) PhosphatidylethanolamineI got this question by my college professor while I was bunking the class.This intriguing question comes from The Composition and Architecture of Membranes in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct option is (a) PHOSPHATIDYLINOSITOL and its derivatives

Easiest explanation: Phosphatidylinositol and its derivatives are important in signal TRANSDUCTION TRIGGERED by HORMONES.

17.

For the determination of fatty acid composition, transesterification is done in a warm aqueous solution of __________(a) KCl+methanol(b) KOH+methanol(c) NaOH+methanol(d) H2O+methanolThis question was addressed to me in examination.The above asked question is from Working with Lipids topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT ANSWER is (c) NaOH+methanol

Explanation: In a WARM solution of methanol+HCl or methanol+NaOH, TRANSESTERIFICATION is DONE.
18.

Which of the following is a polar derivative of cholesterol?(a) Bile salt(b) Oestrogen(c) Vitamin D(d) ProgesteroneThe question was posed to me in homework.This interesting question is from Storage Lipids topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct ANSWER is (a) BILE salt

The BEST explanation: Bile salt is a polar derivative of CHOLESTEROL.

19.

Which out of the following is not mediated transport?(a) Facilitated diffusion(b) Primary active transport(c) Secondary active transport(d) Simple diffusionI had been asked this question in class test.This question is from Solute Transport across Membranes in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT OPTION is (d) SIMPLE diffusion

For explanation I WOULD say: Simple diffusion is not mediated TRANSPORT.
20.

Which of the following vitamin is derived from cholesterol?(a) A(b) B(c) C(d) DThis question was addressed to me in final exam.I'm obligated to ask this question of Lipids as Signals, Cofactors, and Pigments in section Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT OPTION is (d) D

For EXPLANATION: Vitamin-D is derived from CHOLESTEROL.
21.

Which of the following is a sphingophospholipid?(a) Lecithin(b) Sphingomyelin(c) Plasmolegen(d) CardiolipinI had been asked this question in an online interview.Enquiry is from Structural Lipids in Membranes in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct OPTION is (b) Sphingomyelin

For explanation: LECITHIN, PLASMOLEGEN and cardiolipin are GLYCEROPHOSPHOLIPIDS.

22.

Semipermeable membrane allows ____________(a) Solute to pass(b) Solution to pass(c) Solvent to pass(d) Proteins to passThis question was addressed to me in examination.My question is taken from Solute Transport across Membranes in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct answer is (C) Solvent to PASS

Easiest explanation: SEMIPERMEABLE membrane ALLOWS solvent to pass.

23.

Which of the following proteins does not function in cell-cell interaction?(a) Integrin(b) Cadherin(c) N-CAM(d) Cytochrome cThis question was posed to me in a job interview.I want to ask this question from Membrane Dynamics topic in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right option is (d) CYTOCHROME c

Easiest explanation: INTEGRAL proteins INTEGRIN, Cadherin, N-CAM and SELECTIN function in cell-cell interaction.

24.

Which would move faster in thin layer chromatography?(a) Beeswax(b) Phosphatidylinositol(c) Cholesterol(d) SteroidI had been asked this question in homework.Enquiry is from Working with Lipids topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct choice is (a) Beeswax

Easy explanation: Least POLAR MOLECULES move faster in THIN layer chromatography.

25.

Which of the following integral membrane protein is a special class of membrane rafts?(a) Caveolin(b) Integrin(c) Cadherin(d) SelectinThe question was posed to me during an interview.The question is from Membrane Dynamics topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right choice is (a) Caveolin

To explain: Caveolin is a SPECIAL CLASS of MEMBRANE RAFTS.

26.

Which of the following is not one of the states of lipids?(a) Para crystalline state(b) Liquid ordered state(c) Liquid disordered state(d) Crystalline stateThis question was posed to me in a national level competition.This is a very interesting question from Membrane Dynamics in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT OPTION is (d) CRYSTALLINE STATE

Easiest explanation: PARA crystalline state, liquid ordered state and liquid disordered state are the states of lipids.

27.

How are the intrinsic proteins in cell membrane distributed?(a) Uniform(b) Random(c) Symmetric(d) AsymmetricI had been asked this question in examination.I need to ask this question from The Composition and Architecture of Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct option is (d) Asymmetric

For EXPLANATION I would say: Intrinsic proteins in CELL membrane are DISTRIBUTED SYMMETRICALLY.

28.

Which of the following does not contain glycerol?(a) Glycerophospholipids(b) Galactolipids(c) Sphingolipids(d) TriacylglycerolsThis question was posed to me during an internship interview.My doubt is from Structural Lipids in Membranes in section Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT OPTION is (c) SPHINGOLIPIDS

The EXPLANATION is: Sphingolipids contain sphingosine instead of GLYCEROL.

29.

Platelet activating factor stimulates the release of which of the following compounds?(a) Vasopressin(b) Serotonin(c) Adrenaline(d) CortisolThis question was addressed to me during an online exam.This intriguing question comes from Structural Lipids in Membranes topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right answer is (B) Serotonin

To explain I would SAY: PLATELET ACTIVATING factor stimulates the release of serotonin.

30.

Which of the following fatty acid has the least melting point?(a) Palmitic acid(b) Stearic acid(c) Arachidonic acid(d) Timnodonic acidI had been asked this question by my college director while I was bunking the class.My question is taken from Storage Lipids in section Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT answer is (d) Timnodonic ACID

For explanation: Timnodonic acid has the least MELTING POINT.

31.

Which of the following types of lipid aggregates has maximum stability?(a) Micelles(b) Bilayer(c) Liposome(d) Myelin sheathI got this question in examination.This is a very interesting question from The Composition and Architecture of Membranes in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct ANSWER is (c) LIPOSOME

To explain: BILAYER is relatively unstable and spontaneously FORMS a third type of aggregate, folds BACK on itself to form a hollow sphere, liposome that has maximum stability in their aqueous environment.

32.

The lipids with potent bio activities derived from isoprenoid precursors are common in __________(a) Vitamin A, K, ubiquinone and dolichol(b) Vitamin A, D, ubiquinone and dolichol(c) Vitamin A, B, D and K(d) Vitamin A, B, K and dolicholThis question was addressed to me by my college professor while I was bunking the class.This question is from Lipids as Signals, Cofactors, and Pigments topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct ANSWER is (a) Vitamin A, K, ubiquinone and dolichol

To explain: Vitamin A, K, ubiquinone and dolichol have in COMMON the lipids with potent bio ACTIVITIES derived from isoprenoid precursors.

33.

When cross sectional area of the head group is greater than that of the acyl side chain, which of the following lipid aggregates formation is favored?(a) Micelles(b) Bilayer(c) Liposome(d) Myelin sheathThis question was posed to me in class test.My question comes from The Composition and Architecture of Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct OPTION is (a) Micelles

Easy EXPLANATION: Micelles FORMATION is favored when cross sectional AREA of the head group is GREATER than that of the acyl side chain.

34.

In which type of chromatography lipids are carried up a silica gel coated pate by a rising solvent front, less polar travels farther than the more polar ones?(a) Absorption chromatography(b) Thin layer chromatography(c) Gas-liquid chromatography(d) HPLCThis question was addressed to me by my school principal while I was bunking the class.My question comes from Working with Lipids in section Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct ANSWER is (B) Thin layer chromatography

Explanation: In TLC, lipids are CARRIED up a SILICA gel coated pate by a rising solvent front, LESS polar travels farther than the more polar ones.

35.

Which of the following is not a phospholipase?(a) A(b) C(c) D(d) KThe question was asked in an online quiz.The above asked question is from Working with Lipids topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT CHOICE is (d) K

The BEST I can EXPLAIN: A, C and D are phospholipases.

36.

Which of the following type structure contains all the three glycosphingolipids?(a) B structure(b) A structure(c) O structure(d) AB structureI had been asked this question in semester exam.This interesting question is from Lipids as Signals, Cofactors, and Pigments topic in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct OPTION is (C) O STRUCTURE

Easy explanation: TYPE O structure has all three glycosphingolipids.

37.

Which of the following is false about lipids?(a) They are either strongly hydrophobic or amphipathic(b) They are more soluble in water(c) Extraction of lipids from tissues require organic solvents(d) They are insoluble in waterI had been asked this question in an interview.I want to ask this question from Working with Lipids in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Correct choice is (b) They are more SOLUBLE in water

Easy EXPLANATION: LIPIDS are LEAST soluble in water. They are AMPHIPATHIC.

38.

Which of the following serves as a specific binding site for the proteins involved in membrane fusion during exocytosis?(a) Phosphatidylinositol(b) Phosphatidylinositol 4, 5-biphosphate(c) Phosphatidylinositol 3, 5-biphosphate(d) Phosphatidylinositol 3, 4-biphosphateI have been asked this question in an interview for internship.My question is based upon Lipids as Signals, Cofactors, and Pigments in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct option is (b) Phosphatidylinositol 4, 5-biphosphate

Best EXPLANATION: Phosphatidylinositol 4, 5-biphosphate in the cytoplasmic face of PLASMA MEMBRANES serves as a specific BINDING site for certain cytoskeletal proteins and for some SOLUBLE proteins involved in membranes fusion during exocytosis.

39.

The number of milligrams of KOH required to neutralize the free and combined fatty acid in one gram of a given fat is called __________(a) Saponification number(b) Iodine number(c) Acid number(d) Polenske numberThis question was addressed to me during an interview for a job.Question is taken from Storage Lipids in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right answer is (a) Saponification number

For explanation: The number of milligrams of KOH required to neutralize the FREE and COMBINED fatty acid in one gram of a GIVEN fat is called the saponification number.

40.

Out of the following which is not a source of glycerol?(a) Adipolysis(b) Glycolysis(c) Glycogenolysis(d) DietThe question was posed to me in an online quiz.This intriguing question originated from Storage Lipids in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right choice is (c) Glycogenolysis

Easiest explanation: Adipolysis, glycolysis and DIET are the SOURCE of GLYCEROL.

41.

Movement of phospholipids to opposite sides is called ____________(a) Facilitated diffusion(b) Lateral diffusion(c) Transverse diffusion(d) Simple diffusionI got this question during an online interview.The origin of the question is Membrane Dynamics in section Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT option is (c) Transverse DIFFUSION

Easiest EXPLANATION: In transverse diffusion, movement of PHOSPHOLIPIDS to opposite sides.

42.

How many types of lipid aggregates are formed when amphipathic lipids are mixed with water?(a) 1(b) 2(c) 3(d) 4I got this question during an internship interview.This is a very interesting question from The Composition and Architecture of Membranes topic in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right answer is (c) 3

For explanation: Micelle, bilayer and liposome are the 3 types of LIPID aggregates are FORMED when amphipathic LIPIDS are mixed with water.

43.

A mixture of fatty acyl methyl esters are separated based on __________(a) Charge(b) Chain length and degree of saturation(c) Molecular weight(d) Ionic sizeThis question was addressed to me during an interview for a job.My question is taken from Working with Lipids topic in section Lipids, Biological Membranes and Transport of Biochemistry

Answer» CORRECT ANSWER is (B) CHAIN length and degree of SATURATION

The explanation is: Based on chain length and degree of saturation, mixture of fatty acyl methyl esters is separated.
44.

Which of the following are the major component of chloroplast membrane of plants and are absent from animal cells?(a) Glycolipids(b) Phospholipids(c) Ether lipids(d) TriacylglycerolsThe question was posed to me by my college professor while I was bunking the class.My query is from The Composition and Architecture of Membranes in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

Right CHOICE is (a) GLYCOLIPIDS

Explanation: Glycolipids are the MAJOR component of CHLOROPLAST membrane of plants and are absent from animal cells.

45.

How many products are obtained by the hydrolysis of phosphatidylinositol by phospholipase C?(a) 1(b) 2(c) 3(d) 4I got this question in quiz.I'm obligated to ask this question of Lipids as Signals, Cofactors, and Pigments in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT OPTION is (b) 2

To explain: Inositol 1, 4, 5-triphosphate and diacylglycerol are the two products obtained by the hydrolysis of phosphatidylinositol by phospholipase C.

46.

Which of the following induces conformational change in protein?(a) Uniport(b) Symport(c) Antiport(d) Facilitated diffusionThe question was posed to me by my college director while I was bunking the class.My question comes from Solute Transport across Membranes topic in division Lipids, Biological Membranes and Transport of Biochemistry

Answer» RIGHT option is (d) FACILITATED DIFFUSION

The explanation: Facilitated diffusion induces a CONFORMATIONAL change in protein.
47.

Na^+ glucose transporter is an example of ____________(a) Symport(b) Antiport(c) Facilitated diffusion(d) ATP driven active transportI have been asked this question in semester exam.This interesting question is from Solute Transport across Membranes topic in portion Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT choice is (a) Symport

To elaborate: SUBSTRATES are MOVED in the same direction across the membrane.

48.

Which of the following is one of the family of immunoglobin like proteins that mediate Ca^+2?(a) N-CAM(b) Integrin(c) Cadherin(d) SelectinThe question was asked in an interview for job.The above asked question is from Membrane Dynamics in division Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The CORRECT OPTION is (a) N-CAM

For explanation: N-CAM is one of the family of IMMUNOGLOBULIN like PROTEINS that mediate Ca^+2.

49.

What leads to the activation of protein kinase C?(a) Release of intracellular Ca^+2 + diacylglycerol(b) Release of intracellular Mg+ + diacylglycerol(c) Release of intracellular Ca^+2 + glycerol(d) Release of intracellular Ca^+2 + triacylglycerolThis question was posed to me during an interview.I want to ask this question from Lipids as Signals, Cofactors, and Pigments in chapter Lipids, Biological Membranes and Transport of Biochemistry

Answer»

The correct ANSWER is (a) Release of intracellular Ca^+2 + DIACYLGLYCEROL

Best explanation: Release of intracellular Ca^+2 + diacylglycerol CAUSES activation of protein kinase C.

50.

Which of the following phospholipids is a component of inner mitochondrial membrane?(a) Plasmologen(b) Cephalin(c) Lecithin(d) CardiolipinThis question was addressed to me in homework.Question is from Structural Lipids in Membranes in section Lipids, Biological Membranes and Transport of Biochemistry

Answer» RIGHT answer is (d) CARDIOLIPIN

The best explanation: Cardiolipin is an ESSENTIAL component of INNER MITOCHONDRIAL membrane.