InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 51. |
A distinct mechanism that usually involves a short segment of DNA with remarkable capacity to move from one location in a chromosome to another, this is calledA. DNA replicationB. DNA transpositionC. DNA hybridizationD. DNA recombination |
| Answer» Correct Answer - b | |
| 52. |
Amino acid sequence, in protein synthesis is decided by the sequence ofA. `c DNA`B. `r- RNA`C. `t -RNA`D. `m-RNA` |
| Answer» Correct Answer - d | |
| 53. |
The sequence of nitrogen bases in a particular region of the non - coding strand of a DNA molecule was founds to CAT GTT TAT CGC. What would be the sequence of nitrogen bases in the mRNA that is synthesized by the corresponding region of the coding strand in that DNAA. GUA CAA AUA GCCB. GTA CAA ATA GCCC. CAU GUU UAU CGCD. CAA GAA TAU GCC |
| Answer» Correct Answer - c | |
| 54. |
Which of the following r-RNAs acts as structural RNA as well as ribozme in bacteria ?A. 5 S rRNAB. 18 S rRNAC. 23 S rRNAD. 5.8 S rRNA |
| Answer» Correct Answer - C | |
| 55. |
Which RNA is having least ageA. m RNAB. t RNAC. r RNAD. None of the above |
| Answer» Correct Answer - a | |
| 56. |
H.G. Khorana was awarded the Nobal Prize for `:`A. Discovering DNAB. Discovering RNAC. Chemical synthesis of geneD. Discovering DNA polymerase |
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Answer» Correct Answer - C Khorana was awarded Nobel prize (1968) for chemical synthesis of gene. |
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| 57. |
Which of the following discoveries resulted in a Nobel PrizeA. Genetic engineeringB. X-rays induce sex-linked recessive lethal mutationsC. Cytoplasmic inheritanceD. Recombination of linked genes |
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Answer» Correct Answer - b b) H.J. Muller (USA) was awarded Nobel prize in 1946 for his contribution on radiation genetics ( By X-rays). |
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| 58. |
Khorana got the Nobel Prize onA. DNA synthesisB. Genetic codeC. Protein synthesisD. Enzyme synthasis |
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Answer» Correct Answer - b b) Marshall Nireberg and Hargobind Khorana have determined which sequence of bases coded is for which amino acds with the help of experiments. |
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| 59. |
The enzyme (s) responsible for the transcription of snRNA in eukaryotes is/areA. RNA polymerase-IB. RNA polymerase-I and IIC. RNA polymerase -IID. RNA polymerase-III |
| Answer» Correct Answer - d | |
| 60. |
Which one the following pairs is correctly matchedA. Ribosomal RNA - carries aminoacids to the site of protein synthesisB. Transcription - process by which mRNA carrise the information from nucleus to the ribosomeC. Translation -Process by which mRNA carries the information from nucleus to the ribosomeD. Anticondon -site of tRNA molecule that contains complementeary bases to the triple code on the mRNA |
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Answer» Correct Answer - d Anticodon are also called codon recognition site. This site has three unpaired bases whose sequence is complementary with a codon in mRNA. |
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| 61. |
DNA as an acidic substance present in nucleus was first identified by ______ in 1869, he named it as _________A. Meischer , nucleinB. Watson and Crick , DNAC. Chargaff, nucleinD. Wilkins and Franklin, double helix |
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Answer» Correct Answer - a (a) |
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| 62. |
DNA produced from RNA is calledA. A-DNAB. B-DNAC. Z-DNAD. c-DNA |
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Answer» Correct Answer - D DNA oroduced from RNA is called c-DNA |
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| 63. |
naturally occurring coding strand composed of alternating C and U residues would result in the formation ofA. A polypeptide containing containing alternating leu and ser residuesB. A polypeptide containing either leu or ser residuesC. A polypeptide containning only ser residuesD. A polypeptide containing only ser resdues |
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Answer» Correct Answer - a a) Because CUC and UCC code for respectively Leucine and Serine. |
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| 64. |
Which of the following be named for DNA produced from RNA ?A. A-DNAB. B-DNAC. C-DNAD. Z-DNA |
| Answer» Correct Answer - C | |
| 65. |
The term genome denotesA. Haploid set of chromosomesB. BivalentC. MonovalentD. Diploid chromosomal set |
| Answer» Correct Answer - A | |
| 66. |
Which one of the following pair of codons is correctly mathed with function or the signal for the particular amino acidA. AUG, ACG -Start//MethionineB. UUA, UCA - LeucineC. GUU, GCU - AlanineD. UAG, UGA - stop |
| Answer» Correct Answer - d | |
| 67. |
Which one of the following pairs of codons is correctly matched with their function of the signal for the particular amino acid ?A. AUG, ACG - Start/methionineB. UUA, UCA - LeucineC. GUU, GCU-AlanineD. UAG, UGA - Stop |
| Answer» Correct Answer - D | |
| 68. |
Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?A. GUU , GCU - AlanineB. UAG , UGA - StopC. AUG , ACG - Start/ methionineD. UUA, UCA - Leucine |
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Answer» Correct Answer - B The group of nucleotides that specifies one amino acid is a code word or codon . The nucleotides of mRNA are arranged as linear sequence of codons , each codon consisting of three successive nitrogenous bases. Three codons UAG UAA and UGA are the termination codons . they do not code for any of the amino acids. In most oranisms AUG codon is the start or initiation codon , i.e. the polypeptide chain starts either with methionine or N- formylmethionine. Leucine - UUA, UUG,CUU, CUC,CUA,CUG. Alanine - GCU ,GCC ,GCA , GCG. GUU - Valine UCA - Serine. |
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| 69. |
An organism uses 20 amino acids while its DNA is made up of 6 types of nitrogenous bases. What would be the minimum size of a codon ?A. 6B. 4C. 3D. 2 |
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Answer» Correct Answer - d |
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| 70. |
During DNA replication, Okazaki fragments are used to elongate :A. The lagging strand towards replication fork.B. The leading strand away from replication fork.C. The leading strand away from the replication fork.D. The leading strand towards replication fork. |
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Answer» Correct Answer - C During DNA replication, Okazaki fragments are used to elongate the lagging strand away from the replication fork. |
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| 71. |
During DNA replication, Okazaki fragments are sued to elongateA. the leading strand towards replication forkB. the lagging strand towards replication fork.C. the leading strand away from replication fork.D. the lagging strand away from the replication fork. |
| Answer» Correct Answer - D | |
| 72. |
During replication of DNA, Okazaki fragments are formed in the direction of `:`A. the lagging strand towards replication forkB. the leading strand away from replication forkC. the lagging strand away from the replication forkD. the leading strand towards replication fork |
| Answer» Correct Answer - C | |
| 73. |
Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against itA. Guanine , Adenine - PurinesB. Adenine, Thymine - PurinesC. Thymine, Uracil - PyrimidinesD. Uracil, Cytosine - Pyrimidines |
| Answer» Correct Answer - b | |
| 74. |
Which one of the following is called polynucleotide joining enzyme ` Or Okazaki fragments are linked by or A foreign DNA and plasmid cut by the same restriction endonuclease can be joined to form a recombinant plasmid usingA. Polymerase IB. Polymerase IIC. LigaseD. Ribonuclease |
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Answer» Correct Answer - c c) the DNA ligase joins the new and old segments of the strand under repair. This makes the damaged DNA strand normal. |
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| 75. |
iRNA is attached to mRNA by itsA. I loopB. II loopC. III loopD. IV loop |
| Answer» Correct Answer - B | |
| 76. |
Clover leaf model of holley for tRNA is a 2D model giving secondary structure. A 3D model showing tertiary structure wasA. L-form model of KlugB. Nucleosome model of kornbergC. Du praw unineme modelD. no such model exists |
| Answer» Correct Answer - A | |
| 77. |
Exon part of m- RNA code forA. proteinB. lipidC. carbohydrateD. phospholipid |
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Answer» Correct Answer - A Exon part of mRNA consists of codons for protein synthesis Exon is the stretch of bases which codes for amino acids , while the non - cording stretches of bases are called intron. |
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| 78. |
Which of the following reunites the exon segments after RNA splicing ?A. RNA polymeraseB. RNA primaseC. RNA ligaseD. RNA protease |
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Answer» Correct Answer - C RNA ligase reunites the exon segments after RNA splicing. |
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| 79. |
Tha charcteristics of a molecular probe are ltbr gt (I) Very long molecule (II) Double stranded (III) DNA or RNA (IV) Complementary to a part of desired gene the correct pair isA. I,IIB. II,IIIC. III,IVD. IV,I |
| Answer» Correct Answer - c | |
| 80. |
Transcription of DNA is aided byA. RNA polymeraseB. DNA polymeraseC. ExonucleaseD. Recombinase |
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Answer» Correct Answer - a a) Enzyme involved in transcription is RNA polymerase - II which consist five polypeptide `alpha,beta,beta,omega` and `sigma`. |
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| 81. |
DNA replication is aided byA. DNA polymerase onlyB. DNA ligase onlyC. Both polymerase and ligaseD. RNA polymerase |
| Answer» Correct Answer - c | |
| 82. |
True replication of DNA is possible due toA. `Hydrogen bondingB. Phosphate backboneC. Complementary base pairing ruleD. None of the above |
| Answer» Correct Answer - c | |
| 83. |
Consider the following nucleic acids 1. DNA, 2. r-RNA, 3. t-RNA, 4. m-RNA choose the correct sequence of their arrangement according to their participation in protein synthesisA. 1,2,3,4B. 2,3,4,1C. 3,2,1,4D. 1,4,2,3 |
| Answer» Correct Answer - D | |
| 84. |
Polyethylene glycol method is used forA. Gene transfer without a vectorB. Biodiesel prodcutionC. Seedless fruit productionD. Energy production from sewage |
| Answer» Correct Answer - a | |
| 85. |
Which was the last humane chromosome to be completely sequenced?A. Chromosome 1B. Chromosome 11C. Chromosome 21D. Chromosome x |
| Answer» Correct Answer - a | |
| 86. |
Which was the last human chromosome to be completely sequenced ?A. Chromose 1B. Chromosome 11C. Chromosome 21D. Chromosome X |
| Answer» Correct Answer - a | |
| 87. |
The source of Taq polymerase used in PCR is a :A. Thermophilic fungusB. Mesophilic fungusC. Thermophilic bacteriumD. halophilic bacterium |
| Answer» Correct Answer - c | |
| 88. |
The figure below shows three steps (A,B,C) of Polymerase Chain Reaction (PCR). Select the option giving correct identification togather with what it represents A. B-Denaturation at a temperature of about `98^(@)C` separating the two DNA strandsB. A- Denaturation at a temperature of about `50^(@)C`C. C- Extension in the presence of heat stable DNA polymeraseD. A- Annealing with two sets of primers |
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Answer» Correct Answer - c c) Expansion proceeds at `72^(@)`C in the presence of Taq DNA polymerase in PCR. |
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| 89. |
Which one is a true statement regarding DNA polymerase used in PCRA. It is used to ligate introduced DNA in recipient cellsB. It serves as a selectable markerC. It is isolated from a virusD. It remains active at high temperature |
| Answer» Correct Answer - d | |
| 90. |
Proteins that hep to open up DNA helix in front of the replication fork in prokaryotes areA. topoisomerasesB. unwindases (helicases)C. polymerase 1D. exonucleases and endocuclease |
| Answer» Correct Answer - B | |
| 91. |
Protein helping in opening of DNA double helix in front of replication fork isA. DNA gyraseB. DNA polymerase -IC. DNA ligaseD. RNA polymerase |
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Answer» Correct Answer - A Protein helping in opening of DNA double helix in front of replication fork is DNA gyrase. |
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| 92. |
There are special proteins that help to open up DNA double helix in front of the replication frok . These protein areA. DNA ligaseB. DNA gyraseC. DNA polymerase ID. None of these |
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Answer» Correct Answer - b b) Gyrase is a type of topoisomerase in E.Coil helps in unwinding of DNA. |
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| 93. |
Durning DNA replication, the strands separate byA. DNA polymeraseB. UnwindaseC. GyraseD. Toposisomerase |
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Answer» Correct Answer - b b) During replication two strands of DNA separate or double stranded DNA uncoils by actioin of enzymes helicase or unwindase enzyme (unwinding protein). |
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| 94. |
DNA strands are antiparallel because of the presence ofA. Peptide bondsB. Disulphide bondsC. H-bondsD. Phosphodiester bonds |
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Answer» Correct Answer - C DNA strands are antiparallel because of H-bonds. |
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| 95. |
Which one of the following hydrolyses internal phosphodiester, bonds in a polynucleotide chainA. LipaseB. ExonucleasesC. EndonucleaseD. Protease |
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Answer» Correct Answer - c c) Restriction endonucleae enzymes cuts the internal phosphodiester bonds of DNA. Endonucleae act only on double stranded by DNA. |
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| 96. |
Which one of the following makes use of RNA as a template to synthesize DNA ?A. Reverse transcriptaseB. DNA dependant RNA polymeraseC. DNA polymeraseD. RNA polymerase |
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Answer» Correct Answer - A In 1970 H Temin and D Baltimore independently discovered the enzyme reverse transcriptase. This enzyme uses RNA as template for the synthesis of cDNA (complementary DNA). |
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| 97. |
Which one of the following hydrolyses internal phosphodiester, bonds in a polynucleotide chainA. LipaseB. ExonucleaseC. EndoncleaseD. Protease |
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Answer» Correct Answer - C Endonuclease hydrolyses internal phosphodiester bonds in a polynucleotide chain. |
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| 98. |
Terminator codon amber isA. UGAB. UAGC. UAAD. UUU |
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Answer» Correct Answer - B The codon Is triplet. 61 codons code for amino acids and 3 codons do not code for any amino acids, hence they function as stop codons or non-sence codons/termination codons. These are UAA (Ochre), UAG (Amber) and UGA (Opal). |
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| 99. |
During protein denaturation which of the following is disruptedA. 2D structureB. 3D structureC. Peptide bondD. AA sequence |
| Answer» Correct Answer - b | |
| 100. |
Where is the enzyme that catalyzes peptide bonding located?A. Larger sub-unit of the ribosomeB. smaller sub-unit of the ribosomeC. leader region of the m-RNAD. t-RNA |
| Answer» Correct Answer - A | |