A microclimate pH, different from the luminal pH exists at the membrane surface.(a) True(b) FalseI had been asked this question during an interview.My question is taken from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology

A microclimate pH, different from the luminal pH exists at the membran

1.	A microclimate pH, different from the luminal pH exists at the membrane surface.(a) True(b) FalseI had been asked this question during an interview.My question is taken from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology
Answer» Right choice is (a) True The EXPLANATION: As SHOWN in experiments, pH absorption curves are less steep and shift to left for BASIC drug and shift to the right for an acidic drug. This led to the hypothesis that a virtual pH ALSO called a microclimate pH exists at the membrane surface.

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