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Which drugs get absorbed in the stomach mostly?(a) Basic drugs(b) Acidic Drugs(c) Neutral drugs(d) No drug gets absorbed in the stomachThis question was addressed to me during an interview for a job.This question is from Drugs Absorption from Non Oral Extravascular Sites topic in chapter Absorption of Drugs of Drug Biotechnology

Answer»

Right ANSWER is (b) Acidic Drugs

The BEST I can explain: Due to the acidic pH of the STOMACH, which is due to the secretion of HCL into the stomach, only acidic DRUG absorption is favoured. But this is possible only if the drugs are soluble in the gastric fluids because most of the drugs get UNIONIZED because of the lower pH.



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