Accumulation of which of the following in the brain leads to phenylketonuria?(a) Phenylpyruvic acid(b) Pyruvic acids(c) Tyrosine(d) PhenylalanineThis question was posed to me during an interview.This interesting question is from Inheritance Principles topic in portion Principles of Inheritance and Variation of Biology – Class 12

Accumulation of which of the following in the brain leads to phenylket

1.	Accumulation of which of the following in the brain leads to phenylketonuria?(a) Phenylpyruvic acid(b) Pyruvic acids(c) Tyrosine(d) PhenylalanineThis question was posed to me during an interview.This interesting question is from Inheritance Principles topic in portion Principles of Inheritance and Variation of Biology – Class 12
Answer» Right answer is (d) Phenylalanine Best explanation: PHENYLKETONURIA is caused DUE to the ACCUMULATION of phenylalanine in the brain of the AFFECTED individuals. Phenylalanine and its derivative are also excreted through the urine because they are POORLY absorbed by the kidneys.

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