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An approach for obtaining a higher-scoring MSA (Multiple Sequence Alignment) by rearranging an existing alignment uses a probability approach called simulated annealing.(a) True(b) FalseI had been asked this question by my college professor while I was bunking the class.I would like to ask this question from Iterative Methods of Multiple Sequence Alignment in section Multiple Sequence Alignment of Bioinformatics

Answer»

Right choice is (a) True

The explanation is: The PROGRAM MSASA (MULTIPLE Sequence Alignment by SIMULATED Annealing) starts with a heuristic MSA (Multiple Sequence Alignment). Further, it CHANGES the alignment by following an algorithm designed to identify changes that increase the alignment score.



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