1.

Discuss The Difference Between Fatty Acid Synthesis And Fatty Acid Oxidation ?

Answer»

Fatty Acid Synthesis:

  1. Occurs in cytosol.
  2. 2-C unit is added through malonyl-ACP (3-C) accompanied by CO2liberation.
  3. ACP is the ACYL group carrier.
  4. β-ketoacyl → β-hydroxyacyl reaction is NADP+ specific.
  5. β-hydroxyacyl intermediate is D-isomer.
  6. Crotonyl → butyryl step is NADP+ specific.
  7. Acetyl CoA carboxylase being an allosteric protein responds to CITRATE and HCO3 as POSITIVE MODIFIERS.

Fatty Acid Oxidation:

  1. Occurs in mitochondria.
  2. 2-C unit is removed in the form of acetyl CoA.
  3. CoA is the acyl group carrier.
  4. β-hydroxyacyl → β-ketoacyl reaction is NAD+ specific.
  5. β-hydroxyacyl intermediate is L-isomer.
  6. Butyryl → crotonyl step is FAD specific.
  7. No such response.

Fatty Acid Synthesis:

Fatty Acid Oxidation:



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