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How do you calculate the rate of excretion by kidneys?(a) Rate of filtration – the rate of secretion – Rate of absorption(b) Rate of filtration + rate of secretion – Rate of absorption(c) Rate of filtration + rate of secretion + Rate of absorption(d) Rate of filtration – the rate of secretion + Rate of absorptionI had been asked this question during an interview for a job.This intriguing question originated from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer»

Correct choice is (b) RATE of filtration + rate of SECRETION – Rate of absorption

Explanation: The rate of excretion through the kidneys is given by Rate of filtration + rate of secretion – Rate of absorption. Absorption is the reabsorption of the drug particles BACK to the SYSTEM thus it gets minus from the filtrated amount and secreted amount.



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