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What is the equation for clearance?(a) Elimination rate / plasma drug concentration(b) Plasma drug concentration/elimination rate(c) 1 / Plasma drug concentration(d) 1 / Elimination rateThis question was posed to me during an interview.My query is from Drugs Excretion topic in section Prodrugs & Excretion of Drugs of Drug Biotechnology |
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Answer» CORRECT OPTION is (a) Elimination rate / plasma drug concentration The best EXPLANATION: Clearance is the hypothetical volume of body fluids containing drug from which the drug will be cleared completely in a specific period of time. It is expressed in ml/min. Clearance is expressed through the equation of elimination rate/plasma drug concentration. |
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