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Identify the major product of Friedel-Crafts acylation of anisole with ethanoyl chloride?(a) 2-Methoxytoluene(b) 4-Methoxytoluene(c) 2-Methoxyacetophenone(d) 4-MethoxyacetophenoneI got this question in semester exam.This key question is from Ethers in portion Alcohols, Phenols and Ethers of Chemistry – Class 12

Answer»

Correct ANSWER is (d) 4-Methoxyacetophenone

Easiest explanation: Anisole undergoes Friedel-Crafts acylation where an acyl GROUP is INTRODUCED at ortho and para position by reaction with acyl chloride with anhydrous AlCl3 as catalyst. The para ISOMER will be the major product.



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