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If the two sequences share significant similarity, it is extremely ______ that the extensive similarity between the two sequences has been acquired randomly, meaning that the two sequences must have derived from a common evolutionary origin.(a) unlikely(b) possible(c) likely(d) relevantI got this question during a job interview.I need to ask this question from Sequence Homology Versus Sequence Similarity and Identity topic in division Pairwise Sequence Alignment of Bioinformatics

Answer»

Right answer is (a) unlikely

To explain I would say: Sequence ALIGNMENT provides inference for the relatedness of two sequences under study. Regions that are aligned but not IDENTICAL represent residue substitutions; regions which RESIDUES from ONE sequence correspond to nothing in the other represent INSERTIONS or deletions that have taken place on one of the sequences during evolution.



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