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In Genetic Algorithm, in the mutation process _______(a) sequence is changed(b) gaps are not inserted(c) sequence is not changed(d) gaps are not rearrangedI got this question in an internship interview.This interesting question is from Iterative Methods of Multiple Sequence Alignment in portion Multiple Sequence Alignment of Bioinformatics |
Answer» CORRECT choice is (c) sequence is not changed The BEST I can explain: In the mutation PROCESS, the sequence is not changed (ELSE it would no longer be an ALIGNMENT), but gaps are inserted and rearranged in an attempt to create a better-scoring MSA. In the gap insertion process, the sequences in a given MSA are divided into two groups based on an estimated phylogenetic tree, and gaps of random length are inserted into random positions in the alignment. |
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