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In the sequence of events in the drug absorption from orally administered solid dosage, which one comes at first?(a) Disintegration(b) Disaggregation(c) Dissolution(d) AbsorptionThis question was posed to me in homework.This interesting question is from Drug Absorption in chapter Absorption of Drugs of Drug Biotechnology

Answer»

Correct answer is (a) Disintegration

Easiest explanation: The solid dosage FORM at first disintegrate into smaller granules or aggregates. Those are then deaggregated to form fine particles. In dissolution, the DRUG is in the solution form and then it GETS ABSORBED.



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