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In which direction does the DNA dependent RNA polymerase catalyse the polymerisation reaction?(a) 3’ → 5’(b) Bidirectional(c) Direction is dependent on the medium(d) 5’ → 3’The question was posed to me during an online exam.I would like to ask this question from Transcription Basics in section Molecular Basis of Inheritance of Biology – Class 12

Answer» CORRECT choice is (d) 5’ → 3’

To explain I WOULD say: The DNA dependent RNA polymerase is an enzyme which has the CAPABILITY to catalyse the polymerisation reaction in the direction of 5’ → 3’ POLARITY. The other strand runs along the

 3’ → 5’ direction of polarity is called as the TEMPLATE strand. Whereas, the 5’ → 3’ strand is called as the coding strand.


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