Here are the latest logs. The CCleaner didn't find ANYTHING to delete.
Malwarebytes' Anti-Malware 1.35
Database version: 1904
Windows 5.1.2600 Service Pack 3

4/8/2009 7:25:33 PM
mbam-log-2009-04-08 (19-25-33).txt

Scan type: Full Scan (C:\|D:\|)
OBJECTS scanned: 184054
Time elapsed: 1 HOUR(s), 15 minute(s), 7 second(s)

Memory Processes Infected: 0
Memory Modules Infected: 0
Registry Keys Infected: 0
Registry Values Infected: 0
Registry Data Items Infected: 0
Folders Infected: 0
Files Infected: 0

Memory Processes Infected:
(No malicious items detected)

Memory Modules Infected:
(No malicious items detected)

Registry Keys Infected:
(No malicious items detected)

Registry Values Infected:
(No malicious items detected)

Registry Data Items Infected:
(No malicious items detected)

Folders Infected:
(No malicious items detected)

Files Infected:
(No malicious items detected)

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 6:03:20 PM, on 4/8/2009
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP3 (6.00.2900.5512)
Boot mode: Normal

Running processes:
D:\WINDOWS\System32\smss.exe
D:\WINDOWS\system32\winlogon.exe
D:\WINDOWS\system32\services.exe
D:\WINDOWS\system32\lsass.exe
D:\WINDOWS\system32\svchost.exe
D:\WINDOWS\System32\svchost.exe
D:\WINDOWS\system32\spoolsv.exe
D:\WINDOWS\Explorer.EXE
D:\Program Files\McAfee\Common Framework\FrameworkService.exe
D:\Program Files\QuickTime\qttask.exe
D:\Program Files\McAfee\Common Framework\udaterui.exe
D:\Program Files\Messenger\msmsgs.exe
D:\Program Files\OpenOffice.org 2.3\program\soffice.exe
D:\Program Files\OpenOffice.org 2.3\program\soffice.BIN
D:\Program Files\McAfee\Common Framework\McTray.exe
D:\WINDOWS\system32\wscntfy.exe
D:\WINDOWS\system32\wuauclt.exe
D:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.mmc.org/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://us.rd.yahoo.com/customize/ie/defaults/sb/msgr9/*http://www.yahoo.com/ext/search/search.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://us.rd.yahoo.com/customize/ie/defaults/sp/msgr9/*http://www.yahoo.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - D:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: &Yahoo! Toolbar Helper - {02478D38-C3F9-4efb-9B51-7695ECA05670} - D:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - D:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: SingleInstance Class - {FDAD4DA1-61A2-4FD8-9C17-86F7AC245081} - D:\Program Files\Yahoo!\Companion\Installs\cpn\YTSingleInstance.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - D:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O4 - HKLM\..\Run: [HPLJ Config] D:\Program Files\Hewlett-Packard\hp LaserJet 1160_1320 series\SetConfig.exe -c Direct -p DOT4_001 -pn "hp LaserJet 1320 PCL 6" -n 1 -l 1033 -sl 120000
O4 - HKLM\..\Run: [QuickTime Task] "D:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [McAfeeUpdaterUI] "D:\Program Files\McAfee\Common Framework\udaterui.exe" /StartedFromRunKey
O4 - HKCU\..\Run: [MSMSGS] "D:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [Windows UPDATE loader] C:\Windows\xpupdate.exe
O4 - HKCU\..\Run: [TomTomHOME.exe] "D:\Documents and Settings\engineering\My Documents\TomTom HOME 2\HOMERunner.exe"
O4 - HKCU\..\Run: [Weather] D:\Program Files\AWS\WeatherBug\Weather.exe 1
O4 - Startup: OpenOffice.org 2.3.lnk = D:\Program Files\OpenOffice.org 2.3\program\quickstart.exe
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - D:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - D:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - D:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - D:\Program Files\Messenger\msmsgs.exe
O10 - UNKNOWN file in Winsock LSP: d:\windows\system32\nwprovau.dll
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft.com/fwlink/?linkid=39204
O16 - DPF: {B8BE5E93-A60C-4D26-A2DC-220313175592} (MSN Games - Installer) - http://cdn2.zone.msn.com/binFramework/v10/ZIntro.cab55579.cab
O16 - DPF: {CB50428B-657F-47DF-9B32-671F82AA73F7} - http://www.photodex.com/pxplay.cab
O16 - DPF: {FD0B6769-6490-4A91-AA0A-B5AE0DC75AC9} (Performance Viewer Activex Control) - https://secure.logmein.com/activex/ractrl.cab?lmi=100
O20 - Winlogon Notify: !SASWinLogon - D:\Program Files\SUPERAntiSpyware\SASWINLO.dll
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - D:\Program Files\Common Files\InstallShield\Driver\1150\Intel 32\IDriverT.exe
O23 - Service: McAfee Framework Service (McAfeeFramework) - McAfee, Inc. - D:\Program Files\McAfee\Common Framework\FrameworkService.exe
O23 - Service: Pml Driver HPZ12 - HP - D:\WINDOWS\system32\HPZipm12.exe

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End of file - 4598 bytes

What should I do next?
hi earmic hows the pc going now , all looks ok

but wait for an expert , harry