Solve : virus has took over my computer?

1.	Solve : virus has took over my computer?
Answer» I will try to explain ,every thing I click on my windows 2000 pro, says file cannot be FOUND,all I can access is the,control panel,and documents.I have trojan remover on it which failed to remove it,I have a-sguared also,I cannot access ANYONE them,I even TRIED to down load new antivirus ,called combofix,it said access to files or folders denied.what can I do,I can download nothing to try to remove it? Thanks for your time KenI'd suggest clean Windows reinstall.before complete clean windows reinstall, try booting windows to the safe MODE with networking and then going to some site like TrendMicro Housecall or Bitdefender free scan or panda active scan and get a check out. Maybe it would detect virus or infection(s) and clean it out...... OTHERWISE you should get clean window install if nothing else happens the way it should.

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