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The quality and quantity of information provided by the PSSM also varies for ________ in the motif.(a) each row(b) each column(c) rows and columns(d) neither the rows nor the columnsThe question was asked during an internship interview.I would like to ask this question from Position topic in portion Multiple Sequence Alignment of Bioinformatics

Answer»

Right answer is (b) each column

Easiest explanation: The QUALITY and quantity of INFORMATION PROVIDED by the PSSM also varies for each column in the motif, and this variation profoundly influences the matches found with sequences. This situation can be accurately DESCRIBED by information theory, and the results can be displayed by a colored graph called a sequence logo.



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