The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________(a) Disintegration time(b) Dissolution time(c) Rate limiting step(d) Gastric Emptying timeI got this question by my college director while I was bunking the class.I would like to ask this question from Drug Absorption in division Absorption of Drugs of Drug Biotechnology

The rate at which drug reaches the systemic circulation is determined

1.	The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________(a) Disintegration time(b) Dissolution time(c) Rate limiting step(d) Gastric Emptying timeI got this question by my college director while I was bunking the class.I would like to ask this question from Drug Absorption in division Absorption of Drugs of Drug Biotechnology
Answer» Correct choice is (c) Rate limiting step For explanation I would say: The rate at which drug reaches the systemic circulation is DETERMINED by the slowest of the various steps involved in the SEQUENCE. Such a step is known as the rate-limiting. Disintegration time is the time required for the drug to be broken down into smaller particles or AGGREGATES. Dissolution time is the time required for all the drug DISINTEGRATED particle to dissolve in the fluid. Gastric emptying time is the emptying time of the stomach.

Discussion

No Comment Found

Related InterviewSolutions

Which form of the drug has the highest bioavailability?(a) Coated tablets(b) Solutions(c) Tablets(d) EmulsionsI have been asked this question at a job interview.This intriguing question comes from Drugs Absorption in section Absorption of Drugs of Drug Biotechnology
The concentration of colorant does not affect the drug solubility.(a) True(b) FalseI had been asked this question during an internship interview.My question is taken from Dosage Form Factors Affecting Drug Absorption topic in section Absorption of Drugs of Drug Biotechnology
How can we study the gastric emptying of a given drug?(a) By mixing the colour with the drug(b) Waiting for the subject man to throw-up(c) Tagging the drug with a radioisotope and scanning the stomach(d) Waiting for the patient to pass fecesI have been asked this question in final exam.I want to ask this question from Drugs Absorption from Non Oral Extravascular Sites topic in chapter Absorption of Drugs of Drug Biotechnology
Which drugs get absorbed in the stomach mostly?(a) Basic drugs(b) Acidic Drugs(c) Neutral drugs(d) No drug gets absorbed in the stomachThis question was addressed to me during an interview for a job.This question is from Drugs Absorption from Non Oral Extravascular Sites topic in chapter Absorption of Drugs of Drug Biotechnology
Which option describes the function of the enteric coated drug?(a) Tough dissolves slowly(b) Thin dissolves completely(c) Dissolves only in alkaline pH of the intestine(d) Shellac coatingI got this question in an online quiz.My doubt is from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology
Several factors such as the thickness of stratum corneum, presence of hair follicles, trauma, hydration of the skin, Grooming, exposure to chemicals determine the passive absorption of drugs from the surface of the skin to below.(a) True(b) FalseThis question was posed to me by my school principal while I was bunking the class.I'm obligated to ask this question of Drugs Absorption from Non Oral Extravascular Sites in section Absorption of Drugs of Drug Biotechnology
Which of the following will be the slowest step in tablet drug absorption?(a) Tablet disintegration to granules(b) Granules disintegration to fine particles(c) Fine particles dissolution(d) Dissolution absorbed into the bloodI have been asked this question in an international level competition.This intriguing question comes from Drugs Absorption topic in chapter Absorption of Drugs of Drug Biotechnology
From the surface of villi protrude smaller projection known as __________(a) Microvilli(b) Villus(c) Fingers(d) CiliaThe question was asked in an online quiz.This is a very interesting question from Drugs Absorption from Non Oral Extravascular Sites topic in chapter Absorption of Drugs of Drug Biotechnology
Which drugs gets mostly absorbed from the mouth?(a) Acidic drugs and lipophilic drugs(b) Lipophilic drugs and neutral drugs(c) Neutral drugs and lipophilic drugs(d) Lipophilic, neutral, basic drugsThis question was posed to me by my college director while I was bunking the class.This interesting question is from Drugs Absorption from Non Oral Extravascular Sites topic in chapter Absorption of Drugs of Drug Biotechnology
Which coating is thin and dissolve rapidly?(a) Sugar coating(b) Film coating(c) Enteric coating(d) Sealing coatingI got this question during an online interview.The doubt is from Drugs Absorption topic in portion Absorption of Drugs of Drug Biotechnology

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment