What is total systemic clearance?(a) Sum of clearance from kidney(b) Sum of clearance from kidney and liver(c) Sum of clearance form non-renal clearances(d) Sum of renal and non-renal clearancesI got this question by my school principal while I was bunking the class.My question is from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology

What is total systemic clearance?(a) Sum of clearance from kidney(b) S

1.	What is total systemic clearance?(a) Sum of clearance from kidney(b) Sum of clearance from kidney and liver(c) Sum of clearance form non-renal clearances(d) Sum of renal and non-renal clearancesI got this question by my school principal while I was bunking the class.My question is from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
Answer» Correct option is (d) SUM of renal and non-renal clearances Easiest EXPLANATION: The sum of INDIVIDUAL clearances by all eliminating organs is called total body clearance or total systemic clearance. It is expressed as the sum of renal and non-renal clearance. This term is APPLIED to all organs involved in drug ELIMINATION.

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