When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.(a) crossings on(b) horizontal(c) diagonal(d) verticalI have been asked this question during an interview.My question is from Methods topic in division Pairwise Sequence Alignment of Bioinformatics

When the two sequences have substantial regions of similarity, many do

1.	When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.(a) crossings on(b) horizontal(c) diagonal(d) verticalI have been asked this question during an interview.My question is from Methods topic in division Pairwise Sequence Alignment of Bioinformatics
Answer» Right choice is (c) diagonal For explanation: The dots LINE up to FORM contiguous diagonal lines, which REVEAL the sequence alignment. If there are interruptions in the middle of a diagonal line, they indicate insertions or deletions. Parallel diagonal lines within the matrix represent REPETITIVE regions of the sequences.

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