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Which among the following is the exact ratio of guanine to cytosine in a DNA double helical structure?(a) 3:2(b) 2:1(c) 1:3(d) 1:1The question was asked by my college professor while I was bunking the class.Query is from Structure of a Polynucleotide Chain in division Molecular Basis of Inheritance of Biology – Class 12

Answer»

Correct choice is (d) 1:1

For explanation I WOULD say: The ratio of the purines (adenine and guanine) to the pyrimidine (thymine and CYTOSINE) should always be equal to 1:1. This is in ACCORDANCE to the CHARGAFF’s rule. The ratio of 1:1 is also based on the base pair rule.



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