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Which of the chromosome mutation leads to Beta-thalassemia?(a) 21(b) 10(c) 11(d) 13I got this question in an online quiz.Query is from Inheritance and Variation Principles in division Principles of Inheritance and Variation of Biology – Class 12

Answer»

Right answer is (c) 11

To elaborate: The mutation in the HBB gene on chromosome NUMBER 11 LEADS to the disorder beta-thalassemia. It is inherited as an AUTOSOMAL recessive trait. The severity of beta-thalassemia DEPENDS upon the nature of the mutation.



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