Which of the following chemical mutagen is both mutagenic to replicating and non-replicating DNA?(a) Acridines(b) Nitrous acid(c) Base analogs(d) Mustard gasI had been asked this question in a job interview.Enquiry is from Inheritance and Variation Principles topic in section Principles of Inheritance and Variation of Biology – Class 12

Which of the following chemical mutagen is both mutagenic to replicati

1.	Which of the following chemical mutagen is both mutagenic to replicating and non-replicating DNA?(a) Acridines(b) Nitrous acid(c) Base analogs(d) Mustard gasI had been asked this question in a job interview.Enquiry is from Inheritance and Variation Principles topic in section Principles of Inheritance and Variation of Biology – Class 12
Answer» Correct answer is (b) Nitrous acid The explanation: Nitrous acid is the chemical mutagen that is both mutagenic to replicating and non-replicating DNA. Acridines are very POWERFUL mutagens and they INDUCE frame shift-mutation or GIBBERISH mutation.

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