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Which of the following drug are over the counter drug?(a) Loratidine(b) Terfenadine(c) Desloratidine(d) FexofenadineI got this question in an internship interview.The origin of the question is Drug Concentration and Pharmacologic Response topic in portion Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Answer»

Right option is (a) LORATIDINE

Best explanation: Loratidine is the only drug of its class available over the counter. It has long lasting effects and does not cause drowsiness because it does not cross the BBB. Terfenadine was formerly USED to treat allergic conditions. In the 1990’s it was removed from the market due to the increased RISK of cardiac ARRHYTHMIAS.



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