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Which of the following drug is of Ethylenediamine class?(a) Mepyramine(b) Diphenhydramine(c) Cyclizine(d) ChlorphenamineI got this question in class test.My query is from Drug Concentration and Pharmacologic Response in portion Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Answer» RIGHT CHOICE is (a) Mepyramine

The best I can explain: Ethylenediamine were the FIRST GROUP of clinically EFFECTIVE H1-antihistamines. Ethylenediamine constitute of mepyramine. Diphenhydramine is of ethanolamine class. Chlorphenamine is of alkylamine class. Cyclizine is of piperazines class, structurally related to the ethylenediamines and the ethanolamines.


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