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Which of the following drug is of Piperazine class?(a) Mepyramine(b) Diphenhydramine(c) Cyclizine(d) ChlorphenamineI had been asked this question during an interview.The question is from Drug Concentration and Pharmacologic Response in section Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Answer»

Correct choice is (c) Cyclizine

For explanation: Ethylenediamine has mepyramine in its class. DIPHENHYDRAMINE is of ethanolamine class. CHLORPHENAMINE is of alkylamine class. Cyclizine is of piperazines class, structurally related to the ethylenediamines and the ethanolamines and thus produces SIGNIFICANT anticholinergic effects. Used most OFTEN to treat motion sickness, vertigo, NAUSEA, and vomiting.



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