Which of the following enzyme is essential for the conversion of histidine to histamine?(a) Histidine amylase(b) Histidine hydrolase(c) Histidine decarboxylase(d) Histidine phosphorylaseI got this question during an interview.My doubt is from Drug Concentration and Pharmacologic Response in chapter Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Which of the following enzyme is essential for the conversion of histi

1.	Which of the following enzyme is essential for the conversion of histidine to histamine?(a) Histidine amylase(b) Histidine hydrolase(c) Histidine decarboxylase(d) Histidine phosphorylaseI got this question during an interview.My doubt is from Drug Concentration and Pharmacologic Response in chapter Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology
Answer» The correct choice is (c) Histidine decarboxylase Explanation: Histamine, when released, causes inflammation by INCREASING vasodilation, capillary permeability, CAUSING smooth MUSCLE contraction, mucus secretion, and parasympathetic nerve stimulation. Occurs primarily in mast cells and basophils.

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