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Which of the following is a classic example of point mutation?(a) Phenylketonuria(b) Sickle cell anaemia(c) Haemophilia(d) ThalassemiaThis question was posed to me during an interview.The doubt is from Inheritance and Variation Principles topic in chapter Principles of Inheritance and Variation of Biology – Class 12

Answer»

The correct option is (b) Sickle cell ANAEMIA

The best explanation: Sickle cell anaemia is a CLASSIC example of point MUTATION. Point mutation generally means that when a SINGLE base pair of DNA changes, a gene mutation occurs that CAUSES the alternation of DNA.



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